Advancements in clinical developments in neo/adjuvant drug therapy for resectable melanoma: ASCO Annual Congress – June 2022

Q4 Medicine Vestnik dermatologii i venerologii Pub Date : 2023-04-05 DOI:10.25208/vdv1382
D. Andreev, A. Zavyalov
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Abstract

In the structure of the incidence of skin tumors, melanoma accounts for a relatively smaller percentage, but that disease is associated with higher risk of an adverse outcome compared with many other malignancies. The study of innovative clinical developments in drug therapy for resectable melanoma, presented at the ASCO Annual Meeting - June 2022, is . The best clinical developments in drug treatment of patients with resectable melanoma were selected for analysis: 1) phase 3 study KEYNOTE-716; 2) PRADO; 3) Neo Trio; 4) SWOG 1512. The presented developments bring extremely promising results for melanoma therapy workflows. The use of cutting edge anti-cancer therapeutics acting on various molecular targets drastically improves the tumor response as well as straitens the total severity of treatment-related adverse events.
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可切除黑色素瘤新/辅助药物治疗的临床进展:ASCO年会- 2022年6月
在皮肤肿瘤的发病率结构中,黑色素瘤所占的比例相对较小,但与许多其他恶性肿瘤相比,该疾病的不良后果风险更高。在2022年6月举行的ASCO年会上,对可切除黑色素瘤药物治疗的创新临床进展进行了研究。选择可切除黑色素瘤患者药物治疗的最佳临床进展进行分析:1)KEYNOTE-716 3期研究;2) 普拉多;3) 新三重奏;4) SWOG 1512。所介绍的进展为黑色素瘤治疗工作流程带来了非常有希望的结果。作用于各种分子靶点的尖端抗癌疗法的使用显著改善了肿瘤反应,并减轻了治疗相关不良事件的总体严重程度。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
40
审稿时长
8 weeks
期刊最新文献
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