What are the maternal risks and pregnancy outcomes after kidney transplantation?

Amer A. Rashed, M. M. Sharaf
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Abstract

Background: Pregnancy after kidney transplantation should be considered as a major concern. Women with transplanted kidney were able to conceive for more than 50 years. Little studies are available highlighting the effects of transplantation on fetal and neonatal health.Purpose: This study was conducted with the purpose of identifying the maternal risks and pregnancy outcomes after kidney transplantation.Methods: Research design: A descriptive (non-experimental) design was used in conducting this study. Tools: Three tools were used during the course of this study, the interviewing questionnaire sheet, maternal risks assessment sheet and pregnancy outcomes sheet.Results: Regarding the maternal risks, there was a significant increase in mean serum creatinine, decrease in estimated glomerular filtration rate, increase in proteinuria, reported abortion rate was 16.3%, pregnancy induced hypertension rate was 20.9%; Among acquired infections, primary herpes simplex was very common with a rate of 18.6% while urinary tract infection rate was 39.5%. Among pregnancy outcomes, the mean gestational age was 35.4 ± 3, mean birth weight was 2,107.8 ± 567.7 and 74.4% of women delivered by C.s. 30.2% of delivered infants experienced incubator admission.Conclusions: The current findings succeeded in answering both study questions.Recommendation: Pregnant women with kidney transplantation should be followed-up more frequent than normal women for early detection of any risks and for obtaining favorable pregnancy outcomes. Women should be monitored frequently for kidney functions, early signs of pregnancy induced hypertension, acquired infections and other maternal risks reported by this study.
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肾移植后的母体风险和妊娠结局是什么?
背景:肾移植后妊娠应被视为一个主要问题。接受肾脏移植的女性能够怀孕超过50年。很少有研究强调移植对胎儿和新生儿健康的影响。目的:本研究旨在了解肾移植术后产妇风险及妊娠结局。方法:研究设计:本研究采用描述性(非实验性)设计。工具:本研究过程中使用了三种工具:访谈问卷、孕产妇风险评估表和妊娠结局表。结果:产妇风险方面,平均血清肌酐升高,肾小球滤过率降低,蛋白尿增高,报告流产率为16.3%,妊高征率为20.9%;获得性感染中,原发性单纯疱疹最为常见,发生率为18.6%,尿路感染发生率为39.5%。在妊娠结局中,平均胎龄为35.4±3,平均出生体重为2,107.8±567.7,74.4%的产妇采用c - s分娩,30.2%的分娩婴儿进入保温箱。结论:目前的研究结果成功地回答了这两个研究问题。建议:肾移植孕妇应比正常妇女更频繁地随访,以便及早发现任何风险并获得良好的妊娠结局。妇女应经常监测肾功能、妊娠高血压的早期症状、获得性感染和本研究报告的其他产妇风险。
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