M. Miri, A. Bahaoddini, M. Jahromi, Farhad Daryanosh, Gholampour
{"title":"The effect of swimming exercise on the expression of CYP17A1 and CYP19A1 genes in ovary tissue of healthy Wistar rats","authors":"M. Miri, A. Bahaoddini, M. Jahromi, Farhad Daryanosh, Gholampour","doi":"10.52547/jmj.16.1.16","DOIUrl":null,"url":null,"abstract":": Introduction: CYP17A1 and CYP19A2 enzymes are key proteins in constructing and regulating steroid hormones such as cortisol, testosterone and estrogen. However, the effect of exercise on these two proteins in ovary tissue has not been investigated yet. The purpose of the present study was to investigate the effect of swimming training on CYP17A1 and CYP19A1 gene expression in ovary tissue of healthy Wistar rats. Materials and Method: Mann-Whitney statistical test used to analyze the data. Results: significantly Conclusion: Regarding the increased expression of CYP17 and CYP19 in ovary tissue after six weeks of swimming and the important role of these proteins in steroid hormone synthesis, it can be argued that swimming is an important non-pharmacological mechanism for treatment of ovulation and infertility problems.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"fSlnmh dnshgh `lwm pzshkhy jhrm","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52547/jmj.16.1.16","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
: Introduction: CYP17A1 and CYP19A2 enzymes are key proteins in constructing and regulating steroid hormones such as cortisol, testosterone and estrogen. However, the effect of exercise on these two proteins in ovary tissue has not been investigated yet. The purpose of the present study was to investigate the effect of swimming training on CYP17A1 and CYP19A1 gene expression in ovary tissue of healthy Wistar rats. Materials and Method: Mann-Whitney statistical test used to analyze the data. Results: significantly Conclusion: Regarding the increased expression of CYP17 and CYP19 in ovary tissue after six weeks of swimming and the important role of these proteins in steroid hormone synthesis, it can be argued that swimming is an important non-pharmacological mechanism for treatment of ovulation and infertility problems.