the the and not and the supervision of a traditional medicine results of showed that the combination of of Termino One herbal could improve the patient's clinical symptoms. According to the patient, this herbal medicine has had the greatest effect in improving cough, sore throat and shortness of breath.
{"title":"A case report: Improving the clinical symptoms of a pregnant woman with Covid 19 with the herbal medicine Termino One","authors":"A. Hashemi, N. Kalani, Mohammad mazaher Bojani","doi":"10.52547/jmj.19.1.1","DOIUrl":"https://doi.org/10.52547/jmj.19.1.1","url":null,"abstract":"the the and not and the supervision of a traditional medicine results of showed that the combination of of Termino One herbal could improve the patient's clinical symptoms. According to the patient, this herbal medicine has had the greatest effect in improving cough, sore throat and shortness of breath.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75565999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Immunoglobulins (Igs) are defensive glycoproteins specifically recognize and destroy pathogens. Immunoglobulin G (IgG) is most abundant Ig in serum has important protective role against infections. Fragment of crystallizable (Fc) in IgG has essential role in pathogens destruction. Determination the physicochemical properties of IgG Fc is useful in well recognition of its function, diagnostic and therapeutic purposes. Bioinformatic is an efficient scientific field uses abundant biological information collected in computers for solving biologic problems. Aim of this study is recognition the physicochemical features of human IgGFc by bioinformatic. Materials and Methods: Amino acid sequence and third structure of reference human IgG were found in PDB (Protein Data Bank) database. Second IgG structure was determined by Protein Homology/analogY Recognition Engine V 2 (Phyre 2) software. Physicochemical properties (felexibility, accessibility and hydrophilicity) of IgGFc fragment were identified by IEDB (Immune Epitope Database) software. Results: According to results of this study, most accessibe, hydrophilic and felexible sites of IgGFc fragment were located to 200 – 450 amino acid sequences. Moreover most accessibe, hydrophilic and felexible positions were overlapped in 291300 and 381400 amino acid sequences and could be most probable locations of epitopes. Conclusion: Physicochemical properties of IgGFc fragment identified in present study are valuable in more exact recognition of IgG functions and its immunogenic epitopes which could be helpful in producing of specific monoclonal anti IgG antibodies for production IgG diagnostic tools, optimizing existing kits, development of similar proteins for diagnostic and therapeutic purposes and phylogenic studies.
{"title":"Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic","authors":"سهیلا روهانی, فاطمه حاجی قاسمی","doi":"10.52547/JMJ.19.1.5","DOIUrl":"https://doi.org/10.52547/JMJ.19.1.5","url":null,"abstract":"Introduction: Immunoglobulins (Igs) are defensive glycoproteins specifically recognize and destroy pathogens. Immunoglobulin G (IgG) is most abundant Ig in serum has important protective role against infections. Fragment of crystallizable (Fc) in IgG has essential role in pathogens destruction. Determination the physicochemical properties of IgG Fc is useful in well recognition of its function, diagnostic and therapeutic purposes. Bioinformatic is an efficient scientific field uses abundant biological information collected in computers for solving biologic problems. Aim of this study is recognition the physicochemical features of human IgGFc by bioinformatic. Materials and Methods: Amino acid sequence and third structure of reference human IgG were found in PDB (Protein Data Bank) database. Second IgG structure was determined by Protein Homology/analogY Recognition Engine V 2 (Phyre 2) software. Physicochemical properties (felexibility, accessibility and hydrophilicity) of IgGFc fragment were identified by IEDB (Immune Epitope Database) software. Results: According to results of this study, most accessibe, hydrophilic and felexible sites of IgGFc fragment were located to 200 – 450 amino acid sequences. Moreover most accessibe, hydrophilic and felexible positions were overlapped in 291300 and 381400 amino acid sequences and could be most probable locations of epitopes. Conclusion: Physicochemical properties of IgGFc fragment identified in present study are valuable in more exact recognition of IgG functions and its immunogenic epitopes which could be helpful in producing of specific monoclonal anti IgG antibodies for production IgG diagnostic tools, optimizing existing kits, development of similar proteins for diagnostic and therapeutic purposes and phylogenic studies.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44809818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davood Alian, Mahdieh Namayande, M. Ghaneian, M. Ehrampoosh, F. Madadizadeh
retrospective descriptive study was performed on of The collected data were analyzed using chi-square test and Pearson correlation coefficient. The Cochran–Armitage test was also performed to evaluate the trend changes in the incidence rate using Winpepi software. rainfall, average humidity and vegetation cover with the number of animal bites (p <0.05). Conclusion: Due to the high incidence of animal bites in Jahrom, it seems necessary to perform basic measures such as training at-risk groups, strengthening the surveillance system and immunization program.
{"title":"Trend of animal bites and related ecological factors in Jahrom county during 2014-2018","authors":"Davood Alian, Mahdieh Namayande, M. Ghaneian, M. Ehrampoosh, F. Madadizadeh","doi":"10.52547/jmj.18.4.5","DOIUrl":"https://doi.org/10.52547/jmj.18.4.5","url":null,"abstract":"retrospective descriptive study was performed on of The collected data were analyzed using chi-square test and Pearson correlation coefficient. The Cochran–Armitage test was also performed to evaluate the trend changes in the incidence rate using Winpepi software. rainfall, average humidity and vegetation cover with the number of animal bites (p <0.05). Conclusion: Due to the high incidence of animal bites in Jahrom, it seems necessary to perform basic measures such as training at-risk groups, strengthening the surveillance system and immunization program.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":"1992 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89013698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamed Nasr Isfahani, L. Rouhi, Noosha Ziya Jahromi, Khalil Khashei
{"title":"Effect of citric acid on p53 and p21 genes expression of the human gastric Adenocarcinoma cell line(AGS)","authors":"Hamed Nasr Isfahani, L. Rouhi, Noosha Ziya Jahromi, Khalil Khashei","doi":"10.52547/jmj.18.4.3","DOIUrl":"https://doi.org/10.52547/jmj.18.4.3","url":null,"abstract":"","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43895923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
مرضیه حق بین, نوید کلانی, الهام رفیعی, نرگس رحمانیان
{"title":"Case Report: A case study of abdominal aortic aneurysm in a bladder cancer patient","authors":"مرضیه حق بین, نوید کلانی, الهام رفیعی, نرگس رحمانیان","doi":"10.52547/JMJ.18.4.6","DOIUrl":"https://doi.org/10.52547/JMJ.18.4.6","url":null,"abstract":"","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42516774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
javad vagharfard, A. Rastgarian, M. Rahmanian, M. pourmokhtari, Mohammad Hasan Damshenas, S. Taban, Hasan Zabetian, N. Kalani, N. Hatami
(n = 20). There was no significant difference between fentanyl and bupivacaine in terms of recovery from nausea and postoperative times (p> 0.05) and differences between bupivacaine-fentanyl and bupivacaine in shivering at 6, 12, 18 and 24 hours postoperatively. There was no significant (p> 0.05).
{"title":"The effect of fentanyl addition to bupivacaine on shivering and vomiting nausea in patients undergoing femoral fracture surgery by spinal anesthesia: A double-blind randomized clinical trial","authors":"javad vagharfard, A. Rastgarian, M. Rahmanian, M. pourmokhtari, Mohammad Hasan Damshenas, S. Taban, Hasan Zabetian, N. Kalani, N. Hatami","doi":"10.52547/JMJ.18.4.2","DOIUrl":"https://doi.org/10.52547/JMJ.18.4.2","url":null,"abstract":"(n = 20). There was no significant difference between fentanyl and bupivacaine in terms of recovery from nausea and postoperative times (p> 0.05) and differences between bupivacaine-fentanyl and bupivacaine in shivering at 6, 12, 18 and 24 hours postoperatively. There was no significant (p> 0.05).","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47548289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case report of scrotal mass the first clinical manifestation of multiple myeloma","authors":"A. Yousefi, R. Inaloo, Hossein Hakimellahi","doi":"10.52547/jmj.18.4.7","DOIUrl":"https://doi.org/10.52547/jmj.18.4.7","url":null,"abstract":"","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47155879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdolreza Sotoodeh Jahromi, M. Moradzadeh, M. Kargar, F. Kafilzadeh, M. Jamalidoust
Despite in and cancer is still the main cause of death worldwide. Crocin, the major carotenoid in saffron, exhibits potent anti-tumor effects in breast, pancreas, and gastric tumors. However, the anti-lymphoma effects of crocin are still unclear, especially in B cell lymphomas. The present study aimed to evaluate the cytotoxic effects of crocin on EBV-infected transformed B cell. an (EBV) The crocin (0.2-200 3 Cell viability and were using MTT, and flow cytometry techniques respectively. Also, miRNA-15a genes expression were determined by real-time PCR. of miRNA-15a3p and miRNA-15a5p in treated cells compared to untreated cells (P>0.05). Conclusions: The results suggested that crocin can be considered for preclinical and also clinical testing in EBV-associated B cell lymphoma treatment. The results showed that due to the effect of crocin in reducing the survival and increasing apoptosis of lymphoma cells and also due to the lack of change in the expression of miRNA-15a, it can be considered as a therapeutic candidate in the treatment of EBV-associated B cell lymphoma.
{"title":"Effect of Crocin on miRNA-15a expression in EBV infected transformed B cell","authors":"Abdolreza Sotoodeh Jahromi, M. Moradzadeh, M. Kargar, F. Kafilzadeh, M. Jamalidoust","doi":"10.52547/jmj.18.3.21","DOIUrl":"https://doi.org/10.52547/jmj.18.3.21","url":null,"abstract":"Despite in and cancer is still the main cause of death worldwide. Crocin, the major carotenoid in saffron, exhibits potent anti-tumor effects in breast, pancreas, and gastric tumors. However, the anti-lymphoma effects of crocin are still unclear, especially in B cell lymphomas. The present study aimed to evaluate the cytotoxic effects of crocin on EBV-infected transformed B cell. an (EBV) The crocin (0.2-200 3 Cell viability and were using MTT, and flow cytometry techniques respectively. Also, miRNA-15a genes expression were determined by real-time PCR. of miRNA-15a3p and miRNA-15a5p in treated cells compared to untreated cells (P>0.05). Conclusions: The results suggested that crocin can be considered for preclinical and also clinical testing in EBV-associated B cell lymphoma treatment. The results showed that due to the effect of crocin in reducing the survival and increasing apoptosis of lymphoma cells and also due to the lack of change in the expression of miRNA-15a, it can be considered as a therapeutic candidate in the treatment of EBV-associated B cell lymphoma.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42159634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
is a major health problem in south of Iran. Therefore, screening programs should be carried out in the urban area of Jahrom for early detection of dyslipidemia. Focusing on overweight and obesity are essential to changing lifestyles among subjects with dyslipidemia.
{"title":"Prevalence of Dyslipidemia and its Determinants in Jahrom: a Population-based Cross-sectional Study","authors":"F. Hooshmand, M. Shojaei, K. Rahmanian","doi":"10.52547/jmj.18.3.49","DOIUrl":"https://doi.org/10.52547/jmj.18.3.49","url":null,"abstract":"is a major health problem in south of Iran. Therefore, screening programs should be carried out in the urban area of Jahrom for early detection of dyslipidemia. Focusing on overweight and obesity are essential to changing lifestyles among subjects with dyslipidemia.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46936739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Transfer of critically ill patients admitted to intensive care units mainly for the purpose of performing diagnostic and therapeutic procedures can be associated with adverse events. The purpose of this study was to determine the relationship between the incidence of adverse events and its associated risk factors during the transfer of ICU Patients. Material & Methods: In this descriptive cross-sectional study, patient data were collected through a checklist of adverse events over a 6-month period. The data were analyzed by descriptive and analytical statistics using SPSS software (version 22). Results: 536 patients (91.2%) had adverse events. The incidence of patient-related, staff-related, and equipmentrelated adverse events was 65.5%, 73.3%, and 7.8%, respectively. The incidence of adverse events was higher in men than women (P= 0.035). The incidence of adverse events in stroke transfer (51.9%) was significantly higher than other methods (P<0.001). Incidence of adverse events in ICU was significantly higher than CCU (P= 0.001). There was a statistically significant correlation between the occurrence of adverse events and the presence of equipment such as oxygen cylinder (P<0.001), cardiac monitor (P=0.047), portable ventilator (P=0.004), pulse oximeter (P<0.001) and bedside railing (P<0.001). Conclusion: The results showed that the incidence of adverse events was high. Organizations must identify and actively address risks during the transition. The use of checklists and communication tools related to data transfer can improve the quality and safety of transfer.
{"title":"Determining the relationship between adverse events and their associated risk factors in the transfer of patients from intensive care units","authors":"Mahdi Asadiyan, M. Heidari, Hamid Reza Dolatkhah","doi":"10.52547/jmj.18.3.1","DOIUrl":"https://doi.org/10.52547/jmj.18.3.1","url":null,"abstract":"Introduction: Transfer of critically ill patients admitted to intensive care units mainly for the purpose of performing diagnostic and therapeutic procedures can be associated with adverse events. The purpose of this study was to determine the relationship between the incidence of adverse events and its associated risk factors during the transfer of ICU Patients. Material & Methods: In this descriptive cross-sectional study, patient data were collected through a checklist of adverse events over a 6-month period. The data were analyzed by descriptive and analytical statistics using SPSS software (version 22). Results: 536 patients (91.2%) had adverse events. The incidence of patient-related, staff-related, and equipmentrelated adverse events was 65.5%, 73.3%, and 7.8%, respectively. The incidence of adverse events was higher in men than women (P= 0.035). The incidence of adverse events in stroke transfer (51.9%) was significantly higher than other methods (P<0.001). Incidence of adverse events in ICU was significantly higher than CCU (P= 0.001). There was a statistically significant correlation between the occurrence of adverse events and the presence of equipment such as oxygen cylinder (P<0.001), cardiac monitor (P=0.047), portable ventilator (P=0.004), pulse oximeter (P<0.001) and bedside railing (P<0.001). Conclusion: The results showed that the incidence of adverse events was high. Organizations must identify and actively address risks during the transition. The use of checklists and communication tools related to data transfer can improve the quality and safety of transfer.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42580633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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