Electroanatomical mapping systems and cardiac arrhythmias: avoiding radiations in pediatric patients

Casale Matteo, Mezzetti Maurizio, Tulino Viviana, Morelli Marco, Ciccarelli Iacopo, M. Simone, Giovagnoli Andrea, Busacca Paolo, Dattilo Giuseppe
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Abstract

Introduction. Cardiac arrhythmias are challenging conditions in pediatric patients, especially in the case of newborns. Most of the tachyarrhythmias in children (90,24%) are atrioventricular reentrant tachycardias (AVRT) and atrioventricular nodal reentrant tachycardias (AVNRT). Although the standard 12-lead ECG maintains high diagnostic value, an invasive electrophysiological study and a catheter ablation are often required. Unfortunately these procedures are burdened by the use of radiations. Materials and Methods. We performed a systematic research in PubMed and Embase. We found 257 articles of interest but we selected only 36 as the most representative. Discussion: The main concerns linked to electrophysiological procedures are the need of fluoroscopy and thus the risk of malignancy as well as dermatitis, cataracts, thyroid diseases and birth defects. Children and especially newborns have a greater life expectancy so their cumulative risk is greater than adults. For this reason the guiding principle in electrophysiological procedures involving radiations in pediatric subjects is as low as reasonably achievable (acronym: ALARA). The development of 3-dimensional (3-D) electroanatomical mapping systems allowed a significant reduction of radiation exposure during ablations. The most recent experiences demonstrated the feasibility and the safety of fluoroless ablation procedures of the most common arrhythmias in children. Conclusions: Cardiac arrhythmias could be very challenging conditions in pediatric patients. Predictors of complications are a body weight <15 kg and an age <4 years so it is clear that newborns are the most difficult patients. It is reasonable, because of these evidences, to approach cardiac arrhythmias pharmacologically in younger subjects. More than 20 years of experiences conducted by the electrophysiologists allow us to encourage the use of the electroanatomical mapping systems, with the objective of reducing the radiation exposure in children, especially when accessory pathways are involved.
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电解剖标测系统与心律失常:儿童患者避免辐射
介绍心律失常在儿科患者中是一种具有挑战性的情况,尤其是在新生儿的情况下。大多数儿童快速性心律失常(90.24%)为房室折返性心动过速(AVRT)和房室结折返性心动过速(AVNRT)。尽管标准的12导联心电图保持较高的诊断价值,但通常需要进行侵入性电生理学研究和导管消融。不幸的是,这些程序因使用辐射而负担沉重。材料和方法。我们在PubMed和Embase进行了系统研究。我们发现了257篇感兴趣的文章,但我们只选择了36篇作为最具代表性的文章。讨论:与电生理程序相关的主要问题是荧光镜检查的需要,以及恶性肿瘤、皮炎、白内障、甲状腺疾病和出生缺陷的风险。儿童,尤其是新生儿的预期寿命更长,因此他们的累积风险比成年人更大。因此,涉及儿科受试者辐射的电生理程序的指导原则是尽可能低的(缩写:ALARA)。三维(3-D)电解剖标测系统的发展使消融过程中的辐射暴露显著减少。最近的经验证明了无氟消融术治疗儿童最常见心律失常的可行性和安全性。结论:心律失常在儿科患者中可能是非常具有挑战性的情况。并发症的预测因素是体重<15公斤和年龄<4岁,因此很明显新生儿是最困难的患者。由于这些证据,对年轻受试者心律失常进行药物治疗是合理的。电生理学家20多年的经验使我们能够鼓励使用电解剖标测系统,目的是减少儿童的辐射暴露,特别是当涉及辅助通路时。
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