Excimer laser atherectomy combined with drug-eluting balloon for lower limb arteriosclerosis obliterans

Y. Diao, Shu-ping Tan, Y. Lan, Peng Li, Jiyang Wang, Guo-dong Ye, Da-jun Li
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Abstract

Objective To evaluate the efficacy of excimer laser atherectomy (ELA) combined with drug-coated balloon (DCB) in the treatment of lower limb arteriosclerosis obliterans. Methods From Sep 2016 to Dec 2018 42 patients (42 limbs) underwent ELA combined with DCB therapy. Results There were 27 males and 15 females.The mean age was (65.7±9.7) years. The average lesion length was (14.3±7.5) cm. The technical success rate was 100% and the remission rate of clinical symptoms was 92.9%. Ankle-brachial index was significantly improved from (0.45±0.15) pre-operation to (0.85±0.13) post-operation (P=0.001). The mean follow-up was 10.9 months. At 3, 6, and 12 months follow-up, the primary patency rate was 95.2%, 92.8% and 84.9%. The 1-year limb salvage rate was 95.2%. Conclusion ELA combined with DCB has a good 1-year results as our data reveal. Key words: Laser, excimer; Arteriosclerosis obliterans; Atherectomy; Drug-coated balloon; Angioplasty
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准分子激光动脉粥样硬化联合药物洗脱球囊治疗下肢动脉硬化闭塞症
目的评价准分子激光动脉粥样硬化切除术(ELA)联合药物包被球囊(DCB)治疗下肢动脉硬化闭塞症的疗效。方法2016年9月至2018年12月,42例患者(42肢)行ELA联合DCB治疗。结果男性27例,女性15例。平均年龄(65.7±9.7)岁。病灶平均长度为(14.3±7.5)cm。技术成功率100%,临床症状缓解率92.9%。踝肱指数由术前(0.45±0.15)显著改善至术后(0.85±0.13)(P=0.001)。平均随访10.9个月。随访3、6、12个月时,原发性通畅率分别为95.2%、92.8%和84.9%。1年肢体保留率为95.2%。结论ELA联合DCB治疗1年疗效良好。关键词:激光;准分子;动脉硬化闭塞性脉管炎;Atherectomy;药物涂层球囊;血管成形术
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