One-dimensional photonic crystal-based biosensor for the detection of glucose concentration in human urine

IF 1.1 4区 物理与天体物理 Q4 NANOSCIENCE & NANOTECHNOLOGY Journal of Nanophotonics Pub Date : 2023-04-01 DOI:10.1117/1.JNP.17.026007
A. El Mouncharih, R. Takassa, O. Farkad, A. Tchenka, F. Elfatouaki, E. Ibnouelghazi, D. Abouelaoualim
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引用次数: 2

Abstract

Abstract. A biosensor structure based on a ternary photonic crystal (TPC) containing a defect is designed and simulated. This proposed biosensor detects the concentration of glucose in human urine. Based on the transfer matrix method, we theoretically studied the transmission spectra through the TPC presuming blood samples with different refractive indices (RIs) infiltrated into the defect layer of the proposed structures. By varying the concentration of glucose in the urine, the RI of the urine is changed, which in turn changes the sensor’s output response; both transmission response and resonance wavelength are affected. We evaluated average sensitivity (S) for the number of periods at different values N for optimization purposes. Our results show that the biosensor has performance parameters for a period value N  =  6. Indeed, a value of 1033 nm of full width at half maximum photonic bandgap can be observed with a S of 965  nm  /  RIU. The quality factor is 1892.542 and the figure of merit is 756.86  RIU  −  1. The proposed biosensor can be a miniaturized structure with extreme sensitivity in the concentration of glucose detection models
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基于一维光子晶体的人体尿液葡萄糖浓度生物传感器
摘要设计并模拟了一种基于含缺陷三元光子晶体(TPC)的生物传感器结构。这种生物传感器可以检测人体尿液中的葡萄糖浓度。基于传递矩阵法,我们从理论上研究了假设不同折射率的血液样本渗透到所提出结构的缺陷层中通过TPC的透射光谱。通过改变尿液中葡萄糖的浓度,尿液的RI被改变,这反过来改变了传感器的输出响应;传输响应和共振波长都受到影响。为了优化,我们评估了不同N值下周期数的平均灵敏度(S)。我们的研究结果表明,生物传感器具有周期值N = 6的性能参数。实际上,当S为965 nm / RIU时,在最大光子带隙的一半处可以观察到1033 nm的全宽值。品质因子为1892.542,品质系数为756.86 RIU−1。所提出的生物传感器可以是一个小型化的结构,在葡萄糖浓度检测模型中具有极高的灵敏度
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来源期刊
Journal of Nanophotonics
Journal of Nanophotonics 工程技术-光学
CiteScore
2.60
自引率
6.70%
发文量
42
审稿时长
3 months
期刊介绍: The Journal of Nanophotonics publishes peer-reviewed papers focusing on the fabrication and application of nanostructures that facilitate the generation, propagation, manipulation, and detection of light from the infrared to the ultraviolet regimes.
期刊最新文献
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