Echocardiographic assessment of left ventricle diastolic dysfunction using transmitral doppler acceleration rate of mitral inflow E-Wave

Adel Alsalman, H. Farhan, Marwa Qasim
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Abstract

Background: Diastolic dysfunction (DD) has a high prevalence in the community. Although it often remains asymptomatic, it can be a significant cause of morbidity and mortality. The assessment of the left ventricular diastolic function (DF) should be an integral part of a routine examination, particularly in patients presenting with dyspnea or heart failure. Patients and Methods: A cross-sectional study started from June 2018 to February 2019. The study was conducted in four medical institutions in Baghdad. Mitral inflow for the assessment of left ventricular DF depending on guideline 2016 was performed. Results: Left ventricular ejection fraction (EF) was higher in a group with normal DF than in the group with DD (P = 0.0001). Mean E/A ratio was higher among patients 2.15 ± 0.48 than in the control Group 1.30 ± 0.50 the difference between them was significant (P = 0.0001). Mean acceleration time (AT) was longer in individual with normal DF (88.23 ± 13.85) than that of patients with LVDD (72.89 ± 8.88), while the acceleration rate in LVDD group (1364.38 ± 277.31) was higher than that in normal LVDF (859.12 ± 275.95). There was a significant difference (P = 0.0001) between the two groups. Conclusion: AT and rate were significantly correlated with DD in normal EF group, but both of them have no relation to the grading of DD.
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二尖瓣血流E波透射多普勒加速率超声心动图评价左心室舒张功能障碍
背景:舒张功能障碍(DD)在社区中有很高的患病率。虽然它通常没有症状,但它可能是发病率和死亡率的重要原因。左心室舒张功能(DF)的评估应该是常规检查的一个组成部分,特别是在出现呼吸困难或心力衰竭的患者中。患者和方法:横断面研究于2018年6月至2019年2月开始。这项研究是在巴格达的四家医疗机构进行的。根据指南2016进行二尖瓣流入评估左室DF。结果:DF正常组左室射血分数(EF)高于DD组(P = 0.0001)。患者平均E/A比(2.15±0.48)高于对照组(1.30±0.50),差异有统计学意义(P = 0.0001)。DF正常组平均加速时间(AT)为88.23±13.85,LVDD组平均加速时间(AT)为72.89±8.88,LVDD组平均加速时间(AT)为1364.38±277.31,高于LVDF正常组(AT)(859.12±275.95)。两组间差异有统计学意义(P = 0.0001)。结论:正常EF组AT、rate与DD显著相关,但与DD分级无关。
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