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Abstract

Cover: In Cole (https://doi.org/10.1002/cptx.77), the image shows ricin co-localization with the endoplasmic reticulum (ER). (A) LSCM ER is shown in blue and ricin co-localization is shown in yellow. (B) STED ER is shown in blue and LSCM ricin colocalization is shown in cyan. (C, D) 3-D enlargement of the area within the black box from panels (A) and (B). The co-localization of ricin with the ER is more accurate due to the improved resolution when imaging the ER with STED. Arrows in panels (C) and (D) correspond to ricin particles that are not co-localized with the ER. Scale bar: (B) 15 μm, (D) 10 μm for the zoomed-in image. Reprinted (adapted) with permission from Herrera et al. (2016). Copyright (2016) Cambridge University Press.