“Music First”: An Alternative or Adjunct to Psychotropic Medications for the Behavioral and Psychological Symptoms of Dementia

Dane L. Shiltz, T. Lineweaver, T. Brimmer, Alex C. Cairns, Danielle S. Halcomb, Jacqueline Juett, Laura Beer, D. Hay, J. Plewes
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引用次数: 13

Abstract

Existing research has primarily evaluated music therapy (MT) as a means of reducing the negative affect, behavioral, and/or cognitive symptoms of dementia. Music listening (ML), on the other hand, offers a less-explored, potentially equivalent alternative to MT and may further reduce exposure to potentially harmful psychotropic medications traditionally used to manage negative behavioral and psychological symptoms of dementia (BPSD). This 5-month prospective, naturalistic, interprofessional, single-center extended care facility study compared usual care (45 residents) and usual care combined with at least thrice weekly personalized ML sessions (47 residents) to determine the influence of ML. Agitation decreased for all participants (p < .001), and the ML residents receiving antipsychotic medications at baseline experienced agitation levels similar to both the usual care group and the ML patients who were not prescribed antipsychotics (p < .05 for medication × ML interaction). No significant changes in psychotropic medication exposure occurred. This experimental study supports ML as an adjunct to pharmacological approaches to treating agitation in older adults with dementia living in long-term care facilities. It also highlights the need for additional research focused on how individualized music programs affect doses and frequencies of antipsychotic medications and their associated risk of death and cerebrovascular events in this population.
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“音乐优先”:治疗痴呆行为和心理症状的精神药物的替代或辅助药物
现有研究主要评估了音乐疗法(MT)作为减少痴呆症负面影响、行为和/或认知症状的一种手段。另一方面,听音乐(ML)提供了一种探索较少、潜在等效的MT替代品,并可能进一步减少接触传统上用于治疗痴呆症(BPSD)负面行为和心理症状的潜在有害精神药物。这项为期5个月的前瞻性、自然主义、跨专业、单中心扩展护理机构研究比较了常规护理(45名居民)和常规护理与每周至少三次的个性化ML会议(47名居民),以确定ML的影响。所有参与者的兴奋感都降低了(p<.001),在基线接受抗精神病药物治疗的ML患者经历了与常规护理组和未服用抗精神病药的ML患者相似的激动水平(药物×ML相互作用p<0.05)。精神药物暴露量没有发生显著变化。这项实验研究支持ML作为治疗长期护理机构中老年痴呆症患者躁动的药理学方法的辅助手段。它还强调了对个性化音乐节目如何影响抗精神病药物的剂量和频率及其相关的死亡和脑血管事件风险进行额外研究的必要性。
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30
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