"Predictors of Negative Symptom Domains in Outpatients with Schizophrenia: A Cross-Sectional Study"

IF 0.8 4区 心理学 Q4 PSYCHOLOGY, CLINICAL Journal of Evidence-Based Psychotherapies Pub Date : 2021-09-01 DOI:10.24193/jebp.2021.2.15
O. Câpâtânâ, M. Fadgyas Stănculete, I. Micluția
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Abstract

"Background: Current research suggests that negative symptoms may not be a unitary construct. Factor analytic studies typically found evidence for a two-factor solution of the negative symptom domain: the expressive and the volitional deficit. This study aimed to investigate whether the two-factor solution of negative symptoms is supported across different instruments of evaluation: PANSS and NSA-16 in outpatients with schizophrenia and to explore the relationship between these domains and sociodemographic, clinical, and metabolic outcomes, routinely assessed in daily practice.Another aim was to determine clinical predictors of negative symptoms domains among these variables. Materials and methods: 107 patients with schizophrenia were included in this cross-sectional study. The Principal Component Analysis was used to identify negative symptom domains and Spearman's rank correlation coefficient and multiple regression analyses were used to assess the relationship between the negative symptom domains and clinical variables. Results: PCA indicated a two-component solution explaining 85.2% of the variance for the NSA-16 subscales, reflecting an expressive deficit and an experiential deficit component. Age of onset of the disease and the cognitive deficit were significant predictors of the expressive deficit , body mass index and the number of admissions in the hospital for the experiential deficit. Conclusions: The current findings indicate that the expressive deficit and the experiential deficit should be considered as distinct domains of the psychopathology and should be rated separately"
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精神分裂症门诊患者阴性症状域的预测因素:一项横断面研究
背景:目前的研究表明,阴性症状可能不是一个单一的概念。因素分析研究通常发现了消极症状领域的双因素解决方案的证据:表达缺陷和意志缺陷。本研究旨在探讨精神分裂症门诊患者的PANSS和NSA-16两种评估工具是否支持阴性症状的双因素解决方案,并探讨这些领域与日常实践中常规评估的社会人口统计学、临床和代谢结果之间的关系。另一个目的是在这些变量中确定阴性症状域的临床预测因子。材料与方法:对107例精神分裂症患者进行横断面研究。采用主成分分析确定负性症状域,采用Spearman等级相关系数和多元回归分析评估负性症状域与临床变量的关系。结果:主成分分析表明,双组分解决方案解释了85.2%的方差的NSA-16子量表,反映了表达缺陷和经验缺陷成分。发病年龄和认知缺陷是表达缺陷、体重指数和因经验缺陷入院人数的显著预测因子。结论:目前的研究结果表明,表达缺陷和经验缺陷应被视为精神病理学的两个不同领域,并应分别进行评估。
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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
20
期刊介绍: The journal is devoted to the advancement of the clinical theory and practice of evidence-based psychotherapies (EBP) (e.g., evidence-based psychological assessments, evidence-based psychological treatments). The journal publishes original papers dealing with EBP and psychology, psychiatry, the medical and mental specialties, and allied areas of science.
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