{"title":"\"Predictors of Negative Symptom Domains in Outpatients with Schizophrenia:\nA Cross-Sectional Study\"","authors":"O. Câpâtânâ, M. Fadgyas Stănculete, I. Micluția","doi":"10.24193/jebp.2021.2.15","DOIUrl":null,"url":null,"abstract":"\"Background: Current research suggests that negative symptoms may not be\na unitary construct. Factor analytic studies typically found evidence for a\ntwo-factor solution of the negative symptom domain: the expressive and the\nvolitional deficit. This study aimed to investigate whether the two-factor\nsolution of negative symptoms is supported across different instruments of\nevaluation: PANSS and NSA-16 in outpatients with schizophrenia and to\nexplore the relationship between these domains and sociodemographic,\nclinical, and metabolic outcomes, routinely assessed in daily\npractice.Another aim was to determine clinical predictors of negative\nsymptoms domains among these variables.\nMaterials and methods: 107 patients with schizophrenia were included in\nthis cross-sectional study. The Principal Component Analysis was used to\nidentify negative symptom domains and Spearman's rank correlation\ncoefficient and multiple regression analyses were used to assess the\nrelationship between the negative symptom domains and clinical variables.\nResults: PCA indicated a two-component solution explaining 85.2% of the\nvariance for the NSA-16 subscales, reflecting an expressive deficit and an\nexperiential deficit component. Age of onset of the disease and the cognitive\ndeficit were significant predictors of the expressive deficit , body mass index\nand the number of admissions in the hospital for the experiential deficit.\nConclusions: The current findings indicate that the expressive deficit and the\nexperiential deficit should be considered as distinct domains of the\npsychopathology and should be rated separately\"","PeriodicalId":43042,"journal":{"name":"Journal of Evidence-Based Psychotherapies","volume":" ","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Evidence-Based Psychotherapies","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.24193/jebp.2021.2.15","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
引用次数: 0
Abstract
"Background: Current research suggests that negative symptoms may not be
a unitary construct. Factor analytic studies typically found evidence for a
two-factor solution of the negative symptom domain: the expressive and the
volitional deficit. This study aimed to investigate whether the two-factor
solution of negative symptoms is supported across different instruments of
evaluation: PANSS and NSA-16 in outpatients with schizophrenia and to
explore the relationship between these domains and sociodemographic,
clinical, and metabolic outcomes, routinely assessed in daily
practice.Another aim was to determine clinical predictors of negative
symptoms domains among these variables.
Materials and methods: 107 patients with schizophrenia were included in
this cross-sectional study. The Principal Component Analysis was used to
identify negative symptom domains and Spearman's rank correlation
coefficient and multiple regression analyses were used to assess the
relationship between the negative symptom domains and clinical variables.
Results: PCA indicated a two-component solution explaining 85.2% of the
variance for the NSA-16 subscales, reflecting an expressive deficit and an
experiential deficit component. Age of onset of the disease and the cognitive
deficit were significant predictors of the expressive deficit , body mass index
and the number of admissions in the hospital for the experiential deficit.
Conclusions: The current findings indicate that the expressive deficit and the
experiential deficit should be considered as distinct domains of the
psychopathology and should be rated separately"
期刊介绍:
The journal is devoted to the advancement of the clinical theory and practice of evidence-based psychotherapies (EBP) (e.g., evidence-based psychological assessments, evidence-based psychological treatments). The journal publishes original papers dealing with EBP and psychology, psychiatry, the medical and mental specialties, and allied areas of science.