Cancer: Evidence Consistent with Epigenetic Carcinogenesis

P. Riley
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引用次数: 1

Abstract

This brief review outlines the accumulated evidence which favours a mechanism of cancer generation that is dependent on defective vertical transmission of the pattern of epigenetic control of genetic expression. This model is based on the initiating lesion involving the process that copies the epigenetic features when stem cells undergo mitosis.
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癌症:与表观遗传学致癌作用一致的证据
这篇简短的综述概述了积累的有利于癌症产生机制的证据,该机制依赖于遗传表达的表观遗传控制模式的缺陷垂直传播。该模型基于干细胞进行有丝分裂时复制表观遗传学特征的起始病变。
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