Huma Khan, Hannah Khan, A. Aziz, Tyler M Ewing, A. Khanani
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引用次数: 1
Abstract
Age-related macular degeneration (AMD) is the leading cause of permanent vision loss in individuals over 50 years of age [1]. Advanced AMD can anatomically present as either neovascular (nAMD) or atrophic AMD. nAMD displays characteristic growth of abnormal vasculature that originates from the choroid or retina, resulting in macular neovascularization (MNV). MNV progression can lead to degeneration of photoreceptors, macular damage, and retinal pigment epithelium disruption [1]. If left untreated, MNV in nAMD can lead to leakage of fluid, lipid, and blood into the outer retina, resulting in irreversible vision loss [1]. Atrophic AMD can progress to geographic atrophy (GA), characterized by atrophy of choriocapillaris, retinal pigment epithelial cells, and macular photoreceptors [1].
期刊介绍：
The worldwide problem of visual impairment is set to increase, as we are seeing increased longevity in developed countries. This will produce a crisis in vision care unless concerted action is taken. The substantial value that ophthalmic interventions confer to patients with eye diseases has led to intense research efforts in this area in recent years, with corresponding improvements in treatment, ophthalmic instrumentation and surgical techniques. As a result, the future for ophthalmology holds great promise as further exciting and innovative developments unfold.
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