Emel Kandaş, M. Edremitlioğlu, U. Demir, G. Erbil, M. H. Sehitoglu
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引用次数: 0
Abstract
Objective: The purpose of this study is to examine the effects of L-carnitine on healing of experimental colon anastomosis injury in
early and late period.
Materials and Methods: Forty female Wistar-Albino rats were used in this study. The rats were divided into 4 groups (CONT-3, CONT-
7, CARN-3, and CARN-7). Injury healing was evaluated for CONT-3 group on the 3rd day and for CONT-7 group on the 7th day
following the anastomosis. Following the operation, CARN-3 and CARN-7 groups were intraperitoneally administered with 100 mg/
kg/day L-carnitine and injury healing was evaluated on the 3rd and 7th days. Injury strength, histological evaluation and antioxidant
enzyme activities and oxidant damage were determined in tissue samples of anastomosis area.
Results: Bursting pressure levels and histological scoring values of CARN-3 group were found to be higher than the CONT-3 group
(p
期刊介绍：
Marmara Medical Journal, Marmara Üniversitesi Tıp Fakültesi tarafından yılda üç kere yayımlanan multidisipliner bir dergidir. Bu dergide tıbbın tüm alanlarına ait orijinal araştırma makaleleri, olgu sunumları ve derlemeler İngilizce veya Türkçe olarak yer alır.
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