Clinical Outcomes of Boston Type-I Keratoprosthesis Implantation: A 4-year Retrospective Study in South Korea

Jiyeon Han, Soomin Lee, Y. Won, D. Lim, Tae-Young Chung
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Abstract

Purpose: To evaluate the long-term results of Boston type-I keratoprosthesis implantation in Korea.Methods: Medical records of six patients (six eyes) who underwent Boston type-I keratoprosthesis implantation between August 2018 and November 2019 were retrospectively reviewed for more than 36 months.Results: The mean follow-up period was 44.3 ± 7.0 months. Best corrected visual acuity (BCVA) improved significantly for all six eyes, from 2.33 ± 0.51 logarithm of the minimum angle of resolution (logMAR) to 0.67 ± 0.59 logMAR. The vision recovered immediately after the surgery in all patients. Retroprosthetic membrane developed in three of the patients, but the visual acuity remained unchanged. Anatomical success was achieved in all six eyes after Boston type-I keratoprosthesis implantation.Conclusions: The long-term analysis of Boston type-I keratoprosthesis implantation showed a faster recovery and improved visual acuity compared with conventional penetrating keratoplasty. Without the use of systemic immunosuppressants, all six eyes showed long-term survival of the Boston keratoprosthesis. Boston type-I keratoprosthesis implantation may be used in patients with recurrent graft failure after keratoplasty. This was the first study investigating the long-term results of Boston keratoprosthesis implantation in Korean patients.
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波士顿i型人工角膜植入术的临床结果:韩国4年回顾性研究
目的:评估在韩国进行Boston I型角膜植入术的长期效果。方法:回顾性分析2018年8月至2019年11月期间接受Boston I类型角膜植入术36个多月的6名患者(6眼)的病历。结果:平均随访时间为44.3±7.0个月。所有6只眼睛的最佳矫正视力(BCVA)均显著提高,从最小分辨角(logMAR)的2.33±0.51对数提高到0.67±0.59 logMAR。所有患者的视力在手术后立即恢复。其中三名患者出现假体后膜,但视力保持不变。Boston I型人工角膜植入术后,6只眼睛在解剖学上均获得成功。结论:Boston I型人工角膜植入术的远期分析显示,与传统穿透性角膜移植术相比,该术恢复更快,视力提高。在不使用全身免疫抑制剂的情况下,所有六只眼睛都显示出波士顿角膜假体的长期存活率。Boston I型人工角膜植入术可用于角膜移植术后复发性移植物衰竭的患者。这是第一项对韩国患者植入波士顿角膜假体的长期结果进行调查的研究。
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