Open science, closed doors: The perils and potential of open science for research in practice

IF 3.5 2区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY ACS Chemical Biology Pub Date : 2022-12-01 DOI:10.1017/iop.2022.61
Richard A. Guzzo, B. Schneider, Haig R. Nalbantian
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引用次数: 15

Abstract

Abstract This paper advocates for the value of open science in many areas of research. However, after briefly reviewing the fundamental principles underlying open science practices and their use and justification, the paper identifies four incompatibilities between those principles and scientific progress through applied research. The incompatibilities concern barriers to sharing and disclosure, limitations and deficiencies of overidentifying with hypothetico-deductive methods of inference, the paradox of replication efforts resulting in less robust findings, and changes to the professional research and publication culture such that it will narrow in favor of a specific style of research. Seven recommendations are presented to maximize the value of open science while minimizing its adverse effects on the advancement of science in practice.
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开放科学,封闭的门:开放科学在实践中研究的危险和潜力
摘要本文倡导开放科学在许多研究领域的价值。然而,在简要回顾了开放科学实践的基本原则及其使用和理由后,本文确定了这些原则与应用研究的科学进步之间的四个不相容之处。不兼容性涉及共享和披露的障碍、过度认同假设-演绎推理方法的局限性和不足、复制努力导致研究结果不那么有力的悖论,以及专业研究和出版文化的变化,使其缩小范围,支持特定的研究风格。提出了七项建议,以最大限度地提高开放科学的价值,同时最大限度地减少其在实践中对科学进步的不利影响。
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来源期刊
ACS Chemical Biology
ACS Chemical Biology 生物-生化与分子生物学
CiteScore
7.50
自引率
5.00%
发文量
353
审稿时长
3.3 months
期刊介绍: ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. The journal also serves as a forum to facilitate the communication between biologists and chemists that will translate into new research opportunities and discoveries. Results will be published in which molecular reasoning has been used to probe questions through in vitro investigations, cell biological methods, or organismic studies. We welcome mechanistic studies on proteins, nucleic acids, sugars, lipids, and nonbiological polymers. The journal serves a large scientific community, exploring cellular function from both chemical and biological perspectives. It is understood that submitted work is based upon original results and has not been published previously.
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