Research progress of nanomaterials in tumor-targeted drug delivery and imaging therapy

Q2 Pharmacology, Toxicology and Pharmaceutics OpenNano Pub Date : 2023-08-31 DOI:10.1016/j.onano.2023.100184
Liu-Ru Fang , Yu-Hua Wang , Zu-Zhao Xiong , Yu-Mei Wang
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引用次数: 1

Abstract

Cancer continues to threaten people's lives and health, and the number of deaths from cancer is very high each year. Traditional treatments such as chemotherapy and surgery are poorly selective and have many side effects. While traditional cancer treatments kill tumor cells, they also damage normal cells and cause a series of toxic side effects. Targeted therapy can compensate for the shortcomings of conventional therapies based on nanomaterials. This paper introduces novel nanomaterials commonly used in tumor-targeted drug delivery as well as imaging therapy, demonstrates the types of active and passive drug delivery systems, and gives examples of research and applications in the past three years. The characteristics of nanomaterials for tumor-targeted therapy and their recent research progress in tumor therapy are summarized. This paper provides theoretical and practical support for nanomaterial-based targeted drug delivery systems and imaging therapy for tumors and provides a reference for the development of nanomaterials for controlled targeted therapy for tumors.

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纳米材料在肿瘤靶向给药和影像学治疗中的研究进展
癌症继续威胁着人们的生命和健康,每年死于癌症的人数非常高。传统的治疗方法,如化疗和手术,选择性差,而且有很多副作用。虽然传统的癌症治疗方法会杀死肿瘤细胞,但它们也会损害正常细胞,并导致一系列毒副作用。靶向治疗可以弥补基于纳米材料的传统治疗的不足。本文介绍了肿瘤靶向药物传递和成像治疗中常用的新型纳米材料,介绍了主动和被动药物传递系统的类型,并给出了近三年来的研究和应用实例。综述了肿瘤靶向治疗纳米材料的特点及近年来在肿瘤治疗中的研究进展。本文为基于纳米材料的肿瘤靶向给药系统和影像学治疗提供了理论和实践支持,为肿瘤可控靶向治疗纳米材料的开发提供了参考。
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来源期刊
OpenNano
OpenNano Medicine-Pharmacology (medical)
CiteScore
4.10
自引率
0.00%
发文量
63
审稿时长
50 days
期刊介绍: OpenNano is an internationally peer-reviewed and open access journal publishing high-quality review articles and original research papers on the burgeoning area of nanopharmaceutics and nanosized delivery systems for drugs, genes, and imaging agents. The Journal publishes basic, translational and clinical research as well as methodological papers and aims to bring together chemists, biochemists, cell biologists, material scientists, pharmaceutical scientists, pharmacologists, clinicians and all others working in this exciting and challenging area.
期刊最新文献
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