Trichodysplasia Spinulosa.

Q3 Medicine Sultan Qaboos University Medical Journal Pub Date : 2024-02-01 Epub Date: 2024-02-28 DOI:10.18295/squmj.5.2023.035
Ayida Al Khalili, Elsa Maciagowski, Khue Nguyen, Kevin A Watters
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Abstract

Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. We report a biopsy-proven case of TS in a male renal transplant patient who presented to a dermatology outpatient clinic in Montreal, Canada, in 2015. He was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications.

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毛发育不良
棘毛发育不良(TS)是一种独特的、罕见的临床和组织学皮肤病,主要在免疫抑制的情况下描述。它是由一种新型的人类多瘤病毒引起的,即毛发育不良棘突相关多瘤病毒(TSPyV)。我们报告了2015年在加拿大蒙特利尔皮肤科门诊就诊的一名肾移植患者经活检证实的TS病例。减少免疫抑制和/或抗病毒治疗是治疗此类病例的主要治疗策略。我们的患者接受了缬甘西洛韦治疗,但没有明显的反应。随后,开始了局部咪喹莫特的试验。对TS的认识可以促进早期诊断和管理,以防止可能的并发症。关键词:棘毛发育不良,免疫抑制,器官移植,人类多瘤病毒。
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
86
审稿时长
7 weeks
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