‘Black Fungus’- An alarming infection during novel coronavirus- A Review

Raneet Das, Jayita Roy, Sumel Ashique
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引用次数: 0

Abstract

Mucormycosis is a most emerging angioinvasive fungal infection of filamentous fungi of zygomycetes class, which on neglecting, causes severe disseminated infection along with significant chances of morbidity and mortality. The diagnosis and treatment remain a bit of a challenging case for the doctors. It has been seen that people who have been suffering from different diseases, such as hematological malignancies, uncontrolled diabetes, or gone through different surgeries, such as hematopoietic stem cell transplant, solid transplantation, are the ones affected by the most. On the other hand, people who have recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) typically show the symptoms of mucormycosis after (1-2) weeks of successful recovery. Standard treatment of mucormycosis is traditionally considered an amphotericin B intravenous (IV) drug as initial therapy, although posaconazole and isavuconazole are also used. The core objective of the review is to typically focus on the area of the sudden cause of effecting mucormycosis on the patients who have already recovered from SARS-CoV-2.
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“黑真菌”-新型冠状病毒期间令人担忧的感染-综述
毛霉病是接合菌纲丝状真菌的一种新兴的血管侵袭性真菌感染,若忽视,可引起严重的播散性感染,发病率和死亡率高。对医生来说,诊断和治疗仍然是一个有点挑战性的案例。据调查,患有恶性血液病、糖尿病等不同疾病或接受过造血干细胞移植、实体移植等不同手术的人受到的影响最大。另一方面,从严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)中康复的人通常在成功康复(1-2)周后出现毛霉病症状。毛霉病的标准治疗传统上被认为是两性霉素B静脉注射(IV)药物作为初始治疗,尽管泊沙康唑和异戊康唑也被使用。审查的核心目标通常是关注对已经从SARS-CoV-2中恢复的患者产生毛霉菌病的突然原因的区域。
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来源期刊
Anti-Infective Agents
Anti-Infective Agents Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
1.50
自引率
0.00%
发文量
47
期刊介绍: Anti-Infective Agents publishes original research articles, full-length/mini reviews, drug clinical trial studies and guest edited issues on all the latest and outstanding developments on the medicinal chemistry, biology, pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical research on antimicrobials, antibacterials, antiviral, antifungal, and antiparasitic agents. Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services.
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