PREDICTION OF THE AVERMECTIN INSECTICIDES HAZARDOUS EFFECT ON HUMAN HEALTH WHEN CONSUMING PLANT PRODUCTS GROWN WITH THE APPLICATION OF FORMULATIONS BASED ON THEM

Abstract

Relevance. In order to conduct agriculture and comply with food standards, it is necessary to create effective systems for controlling the content of pesticides active ingredients in agricultural crops, the food products quality, and assessing the risk of consuming food that may contain pesticide residues.Objective: forecasting and assessment of the risk of consuming products contaminated with avermectin insecticides hazardous effect on human health.Materials and methods. The actual content of abamectin and emamectin benzoate in vegetable, grain, stone fruits, berries, grapes, soybeans and green mass of plants was determined by the methods of gas chromatography and high-performance liquid chromatography. The τ50 of the studied insecticides and the integral index of danger when using products contaminated by them were calculated. Results. According to its stability in agricultural crops (grapes, cabbage, peaches, cherries) emamectin benzoate pertained to the 4th hazardous class (not stable); abamectin – to class 3 (moderately stable compounds) in grapes, pears, nuts, strawberries, apples, tomatoes; to the 4th class (non-persistent compound) – in cucumbers, eggplants, soybeans. Abamectin and emamectin belong to the 2nd hazardous class according to integral index of danger when using pesticide-contaminated products value – dangerous. This is due to its high toxicity for warm-blooded animals and humans and a wide range of crops on which formulations based on the studied compounds are allowed to be used.Conclusion. It was established that abamectin and emamectin benzoate belong to moderately persistent (3rd hazard class) and non-persistent (4th hazard class) pesticides according to their persistence in agricultural plants, respectively, and according to the value of integral index of danger when using pesticide-contaminated products value, both studied compounds belong to the 2nd class (dangerous).