Comparison of Cinnamon and Vitex on Improving Sexual Function in Postmenopausal Women: A Triple-blind Randomized Clinical Trial

IF 1 Q4 PHARMACOLOGY & PHARMACY Jundishapur Journal of Natural Pharmaceutical Products Pub Date : 2022-10-30 DOI:10.5812/jjnpp-128406
Tanya Koliji, Zohra Keshavarz, F. Mojab, M. Nasiri, E. Zare
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Abstract

Background: Sexual dysfunction is one of the most common problems following menopause. This study aimed to evaluate the effect of cinnamon and vitex on improving sexual function in postmenopausal women. Methods: This study was a randomized triple-blind clinical trial with a control group. Randomized sampling was used to allocate postmenopausal women into three cinnamon, vitex, and placebo groups of 35. A sexual function index was utilized before and two and three months after the intervention to assess sexual functioning. SPSS version 21 software was used for analysis. Results: The mean age was 54.45 ± 3.73 years. The overall sexual function score in the two cinnamon and vitex groups showed a statistically significant difference before and after treatment compared to the placebo group (P < 0.00). In the vitex group, sexual desire (P = 0.00) and arousal (P = 0.02) increased significantly compared to pre-intervention, and this significant increase was observed in the cinnamon group in lubricity (P = 0.00) and sexual satisfaction (P = 0.03). Conclusions: Cinnamon and vitex are effective medicinal herbs to alleviate sexual function.
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肉桂和Vitex改善绝经后妇女性功能的比较:一项三盲随机临床试验
背景:性功能障碍是绝经后最常见的问题之一。本研究旨在评价肉桂和牡荆对改善绝经后妇女性功能的作用。方法:本研究为随机三盲临床试验,设对照组。采用随机抽样将绝经后妇女分为三组,每组35人,分别为肉桂组、维生素组和安慰剂组。在干预前以及干预后两个月和三个月使用性功能指数来评估性功能。采用SPSS 21版软件进行分析。结果:平均年龄54.45±3.73岁。与安慰剂组相比,肉桂和牡荆两组治疗前后的总体性功能评分显示出统计学上的显著差异(P<0.00)。牡荆组的性欲(P=0.00)和唤醒(P=0.02)与干预前相比显著增加,肉桂组在润滑性(P=0.00)和性满意度(P=0.03)方面有显著提高。结论:肉桂和牡荆是缓解性功能的有效药材。
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