A 12-week, whole-food carbohydrate-restricted feasibility study in overweight children

C. Zinn, O. Schmiedel, J. McPhee, N. Harris, M. Williden, Mark C. Wheldon, D. Stride, G. Schofield
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引用次数: 3

Abstract

Background: Childhood obesity is a global health concern. Conventional nutrition guidelines have come under scrutiny in helping to achieve long-term healthy weight. An alternative carbohydrate-restricted, higher fat approach has shown to be effective in adults, but research is limited in youth. Aim: To assess the feasibility of a 12-week whole-food, carbohydrate-restricted diet on weight loss and metabolic health. Setting: Overweight children aged 8–13 years. Methods: In this single-arm study, 25 overweight children were provided with whole-food, carbohydrate-restricted dietary guidelines. Primary outcomes – dietary acceptability, adherence and affordability – were assessed qualitatively weekly (telephone) and post-intervention (focus groups). Secondary outcomes – Body mass index (BMI), waist circumference, lipids and glycaemic control measures – were assessed at 0 and 12 weeks. Change scores were analysed using the t-statistic and interpreted using the statistical significance threshold, p < 0.05. Results: Overall, dietary acceptability was mostly positive, and reports of affordability by parents were mixed. Attrition rates were high (48%); adherence was influenced, positively and negatively, by levels of support from friends and family. Completing children reduced BMI by 2.1 ± 1.5 kg.m2 (p < 0.05). Key blood parameter changes included a reduction in triglycerides (−0.17 ± 0.48 mmol/L; p = 0.242) and an increase in high-density lipoprotein (HDL) cholesterol (0.24 ± 0.19 mmol/L; p < 0.05). Conclusion: Children achieved some weight loss and health outcome success using this dietary approach. For sustainable weight loss maintenance, full family and health professional support, particularly on a more intensive level at the start, may be required.
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对超重儿童进行为期12周的全碳水化合物限制可行性研究
背景:儿童肥胖是一个全球性的健康问题。传统的营养指南在帮助实现长期健康体重方面受到了严格审查。另一种限制碳水化合物、高脂肪的方法已被证明对成年人有效,但对年轻人的研究有限。目的:评估为期12周的全食物、碳水化合物限制饮食对减肥和代谢健康的可行性。研究对象:8-13岁超重儿童。方法:在这项单臂研究中,25名超重儿童被提供了全食物、碳水化合物限制饮食指南。主要结果——饮食可接受性、依从性和可负担性——每周(电话)和干预后(焦点小组)进行定性评估。次要结果——体重指数(BMI)、腰围、血脂和血糖控制措施——在0周和12周进行评估。改变评分采用t统计量分析,采用统计学显著性阈值解释,p < 0.05。结果:总体而言,饮食可接受性大多是积极的,父母的负担能力报告好坏参半。流失率高(48%);依从性受到朋友和家人支持水平的积极和消极影响。完成治疗的儿童BMI降低2.1±1.5 kg。M2 (p < 0.05)。关键血液参数变化包括甘油三酯降低(- 0.17±0.48 mmol/L;p = 0.242),高密度脂蛋白胆固醇升高(0.24±0.19 mmol/L;P < 0.05)。结论:使用这种饮食方法,儿童取得了一定的体重减轻和健康结果的成功。为了可持续地维持减肥,可能需要全面的家庭和健康专业人员支持,特别是在开始时更密集的支持。
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发文量
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审稿时长
17 weeks
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