Candida guilliermondii Peritonitis During Peritoneal Dialysis. Case Report and Literature Review

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Clinical Management Issues Pub Date : 2023-05-25 DOI:10.7175/cmi.v17i1.1537

A. Mastroianni, V. Vangeli, M. Mauro, Francesca Greco, Filippo Urso, R. Manfredi, S. Greco

引用次数: 0

Abstract

Peritonitis is the most frequent complication of peritoneal dialysis (PD) and 3–6% of episodes have fungal origin. Candida guilliermondii is an uncommon species of Candida with invasive behavior in patients affected by severe underlying disorders or using indwelling vascular devices.Here we report the case of an 84-year-old woman undergoing outpatient PD for 4 years who had fever, chills, and diffuse increasing abdominal pain. After empiric antimicrobial therapy, based on teicoplanin in the dialytic circuit plus oral ciprofloxacin plus fluconazole, the patient was hospitalized. Afterwards, the culture from the peritoneal fluid showed the presence of C. guilliermondii.PD-related fungal peritonitis is an infrequent event, but the morbidity and mortality rates are significant. In this scenario, appropriate prevention strategies including antifungal prophylaxis during antibiotic treated bacterial peritonitis should be evaluated.

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腹膜透析期间的吉利蒙地假丝酵母菌腹膜炎。病例报告及文献复习

腹膜炎是腹膜透析（PD）最常见的并发症，3-6%的发作源于真菌。吉列蒙氏假丝酵母是一种罕见的假丝酵母，在患有严重潜在疾病或使用留置血管装置的患者中具有侵袭性行为。在这里，我们报告了一例84岁的女性接受门诊帕金森病治疗4年的病例，她有发烧、发冷和弥漫性腹痛。经经验性抗菌治疗，以透析回路中的替考拉宁加口服环丙沙星加氟康唑为基础，患者住院治疗。之后，腹膜液培养物显示存在C.guilliermondii。PD相关的真菌性腹膜炎是一种罕见的事件，但发病率和死亡率很高。在这种情况下，应评估适当的预防策略，包括抗生素治疗细菌性腹膜炎期间的抗真菌预防。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinical Management Issues MEDICINE, GENERAL & INTERNAL-

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审稿时长

13 weeks

期刊介绍： Clinical Management Issues is an open access, peer-reviewed journal published by SEEd Medical Publishers (online ISSN = 2283-3137). The aim of the published case reports is to expand medical knowledge, allowing a better explanation of the practical application of a clinical guideline, or including an up-to-date review of medical knowledge in that field, or helping doctors to make better decisions in a “grey area”, or explaining how to manage a disease with an integrated approach between different specialists involved. Clinical Management Issues also publishes unusual case reports (i.e. unusual side effects or adverse interactions involving medications, unexpected or unusual presentations of a disease, etc.), articles on clinical management of a disease, case series, editorials, and brief reports. Acceptance rate of submitted articles is about 90%. Content is subject to peer-review and is editorially independent. This journal provides immediate open access to all of its articles (both HTML and PDF versions). Authors are asked to state any professional and financial situations that might be perceived as causing a conflict of interest with respect to integrity of content. The Declaration of Financial Competing Interests, that should be filled, signed and sent to the Publisher, is downloadable here.