Soundararajan Sowmiya , Ragothaman Prathiviraj , Joseph Selvin , R. Jasmine
{"title":"Analysis of evolutionary imprints among the gut bacteria in phytobiotic supplemented Gallus gallus domesticus","authors":"Soundararajan Sowmiya , Ragothaman Prathiviraj , Joseph Selvin , R. Jasmine","doi":"10.1016/j.angen.2023.200153","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>The gut microbiota<span> is an essential part of metabolism, assists in the breakdown of complex carbohydrates, proteins and lipids that enter into the </span></span>digestive tract. Numerous microbial metabolites thus produced can have local and systemic effects which may influence health positively or negatively. The microbial population's dominance in the gut depends on the number of compounds present in the organ. Hence we have focused on analyzing the role of </span><span><em>Moringa oleifera</em></span><span><span> as phytobiotic supplementation in enhancing the beneficial gut microbiota in chicken models. Probiotics improve gut health in chickens through several mechanisms, including tight junction enhancement, </span>nutrient uptake<span>, niche colonization and co-aggregation with enteropathogens. The bacteria from the gut samples obtained from </span></span><em>M.oleifera</em><span> treated chickens were analyzed for various standard morphological and biochemical tests<span>, genotypic classification using 16S rRNA gene sequencing and evaluation of evolutionary marks among the gut bacteria to determine whether they fit the criteria for probiotic traits. A variety of the consequences of beneficial gut microorganisms for hosts could attribute to bacterial communities' processes and the host's capacity for influencing the same processes. According to our study, phylogenetic analysis and taxonomy of the host significantly shape the intestinal flora across a range of host taxonomic levels. However, host ecology (</span></span><em>i.e.</em>, diet) can further alter these gut flora, particularly in the case of many closely related host species.</p></div>","PeriodicalId":7893,"journal":{"name":"Animal Gene","volume":"29 ","pages":"Article 200153"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Animal Gene","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S235240652300009X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
The gut microbiota is an essential part of metabolism, assists in the breakdown of complex carbohydrates, proteins and lipids that enter into the digestive tract. Numerous microbial metabolites thus produced can have local and systemic effects which may influence health positively or negatively. The microbial population's dominance in the gut depends on the number of compounds present in the organ. Hence we have focused on analyzing the role of Moringa oleifera as phytobiotic supplementation in enhancing the beneficial gut microbiota in chicken models. Probiotics improve gut health in chickens through several mechanisms, including tight junction enhancement, nutrient uptake, niche colonization and co-aggregation with enteropathogens. The bacteria from the gut samples obtained from M.oleifera treated chickens were analyzed for various standard morphological and biochemical tests, genotypic classification using 16S rRNA gene sequencing and evaluation of evolutionary marks among the gut bacteria to determine whether they fit the criteria for probiotic traits. A variety of the consequences of beneficial gut microorganisms for hosts could attribute to bacterial communities' processes and the host's capacity for influencing the same processes. According to our study, phylogenetic analysis and taxonomy of the host significantly shape the intestinal flora across a range of host taxonomic levels. However, host ecology (i.e., diet) can further alter these gut flora, particularly in the case of many closely related host species.
Animal GeneAgricultural and Biological Sciences-Insect Science
自引率
0.00%
发文量
16
期刊介绍:
Gene Reports publishes papers that focus on the regulation, expression, function and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses. Gene Reports strives to be a very diverse journal and topics in all fields will be considered for publication. Although not limited to the following, some general topics include: DNA Organization, Replication & Evolution -Focus on genomic DNA (chromosomal organization, comparative genomics, DNA replication, DNA repair, mobile DNA, mitochondrial DNA, chloroplast DNA). Expression & Function - Focus on functional RNAs (microRNAs, tRNAs, rRNAs, mRNA splicing, alternative polyadenylation) Regulation - Focus on processes that mediate gene-read out (epigenetics, chromatin, histone code, transcription, translation, protein degradation). Cell Signaling - Focus on mechanisms that control information flow into the nucleus to control gene expression (kinase and phosphatase pathways controlled by extra-cellular ligands, Wnt, Notch, TGFbeta/BMPs, FGFs, IGFs etc.) Profiling of gene expression and genetic variation - Focus on high throughput approaches (e.g., DeepSeq, ChIP-Seq, Affymetrix microarrays, proteomics) that define gene regulatory circuitry, molecular pathways and protein/protein networks. Genetics - Focus on development in model organisms (e.g., mouse, frog, fruit fly, worm), human genetic variation, population genetics, as well as agricultural and veterinary genetics. Molecular Pathology & Regenerative Medicine - Focus on the deregulation of molecular processes in human diseases and mechanisms supporting regeneration of tissues through pluripotent or multipotent stem cells.