Reviewing Treatments for Cocaine Consume Problems: The Gabapentinoid Alternative

IF 1.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Open Access Journal of Clinical Trials Pub Date : 2021-09-23 DOI:10.2147/OAJCT.S327934
Gabriel C Quintero Garzola
{"title":"Reviewing Treatments for Cocaine Consume Problems: The Gabapentinoid Alternative","authors":"Gabriel C Quintero Garzola","doi":"10.2147/OAJCT.S327934","DOIUrl":null,"url":null,"abstract":"Background: Cocaine use disorder is a worldwide problem. Presently, however, no adequate treatments exist. Gabapentin has been explored recently as an alternative for treating different substance use disorders, including cocaine. Methods: The aim of the present paper is to assess the effectiveness of gabapentin for treating cocaine use disorders. For this purpose, a systematic review of the literature was performed using the publication database, PubMed, with search limits from January 1, 1983 to February 28, 2018. The search terms used were combined as follows: “gabapentin” AND “cocaine”. Initially, 41 articles were identified, with additional 23 articles identified through reference exploration or web search. These 23 complementary articles relate mainly to the general description of gabapentin and discussion. After the analysis of the titles and abstracts, 18 references were removed, resulting in 46 articles for further analysis. Results and Discussion: Gabapentin is inadequate for treating cocaine dependence and relapse, and alleviating the subjective effects of cocaine. More research is necessary for exploring gabapentin alleviation of cocaine intoxication, and further investigation is required for confirming the gabapentin’s utility for treating cocaine addiction.","PeriodicalId":19500,"journal":{"name":"Open Access Journal of Clinical Trials","volume":"13 1","pages":"45-60"},"PeriodicalIF":1.4000,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Access Journal of Clinical Trials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/OAJCT.S327934","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Cocaine use disorder is a worldwide problem. Presently, however, no adequate treatments exist. Gabapentin has been explored recently as an alternative for treating different substance use disorders, including cocaine. Methods: The aim of the present paper is to assess the effectiveness of gabapentin for treating cocaine use disorders. For this purpose, a systematic review of the literature was performed using the publication database, PubMed, with search limits from January 1, 1983 to February 28, 2018. The search terms used were combined as follows: “gabapentin” AND “cocaine”. Initially, 41 articles were identified, with additional 23 articles identified through reference exploration or web search. These 23 complementary articles relate mainly to the general description of gabapentin and discussion. After the analysis of the titles and abstracts, 18 references were removed, resulting in 46 articles for further analysis. Results and Discussion: Gabapentin is inadequate for treating cocaine dependence and relapse, and alleviating the subjective effects of cocaine. More research is necessary for exploring gabapentin alleviation of cocaine intoxication, and further investigation is required for confirming the gabapentin’s utility for treating cocaine addiction.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
回顾可卡因消费问题的治疗:加巴喷丁类药物的替代品
背景:可卡因使用障碍是一个全球性的问题。然而,目前还没有足够的治疗方法。加巴喷丁最近被探索作为治疗包括可卡因在内的不同物质使用障碍的替代品。方法:评价加巴喷丁治疗可卡因使用障碍的疗效。为此,使用出版物数据库PubMed对1983年1月1日至2018年2月28日的文献进行了系统综述,检索范围为。使用的搜索词组合如下:“加巴喷丁”和“可卡因”。最初,共确定了41篇文章,另有23篇文章是通过参考资料探索或网络搜索确定的。这23篇补充文章主要涉及加巴喷丁的一般描述和讨论。在对标题和摘要进行分析后,删除了18篇参考文献,产生了46篇文章供进一步分析。结果与讨论:加巴喷丁不足以治疗可卡因依赖和复发,也不足以减轻可卡因的主观影响。需要更多的研究来探索加巴喷丁对可卡因中毒的缓解作用,还需要进一步的研究来证实加巴喷汀对治疗可卡因成瘾的效用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Open Access Journal of Clinical Trials
Open Access Journal of Clinical Trials MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
3.90
自引率
0.00%
发文量
2
审稿时长
16 weeks
期刊最新文献
A Multidomain Intervention Program for Older People with Dementia: A Pilot Study Randomized Clinical Trial Comparing Insulin Fast Dissolving Films versus Control Group for Anosmic Patients for Improving Their Health and Social Qualities of Life Treatment of Oropharyngeal Symptoms: A Prospective, Single-Dose, Placebo-Controlled, Randomized Clinical Trial Post-Trial Considerations for an Early Phase Optogenetic Trial in the Human Brain Reviewing Treatments for Cocaine Consume Problems: The Gabapentinoid Alternative
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1