Study of Correlation between Right Ventricular Ejection Fraction with Left Ventricular Ejection Fraction in Patients of Chronic Heart Failure with Diabetes, using Two-dimensional Echocardiography

Vandan Shah, S. Mane, R. Khyalappa
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Abstract

Diabetes is one of the most significant health issues. Patients with type 2 diabetes mellitus (DM) are more susceptible to an elevated cardiovascular risk, including heart failure. Echocardiography should help in the early identification of these myocardial abnormalities that would help properly treat these individuals. The study was conducted over 18 months and focused on patients with diabetes and chronic heart failure who met inclusion and exclusion criteria. Ethical approval was obtained, and all patients provided their consent to participate in the study. The participants underwent a two-dimensional echocardiogram to assess their heart function, and relevant laboratory tests, imaging results, and information about medications received during their hospitalization were recorded. As per The New British Society of Echocardiography criteria, 64 patients had impaired left ventricular ejection fraction (LVEF), and 31 had severely impaired LVEF. The majority of the patients with impaired LVEF, 53%, also had impaired right ventricular ejection fraction (RVEF). Of 31 patients with severely impaired LVEF, 58% also had severely impaired RVEF. The association between LVEF and RVEF is statistically significant (P < 0.05). There is a positive correlation between LVEF (%) and RVEF (%), which was statistically significant (P < 0.05). Severe dysfunction in LVEF is also present in patients with severe dysfunction of RVEF. The majority of patients who had reduced LVEF also had reduced RVEF, and this association was significant. While there was a correlation between glycosylated hemoglobin levels and both LVEF and RVEF, it was not statistically significant. Hence, patients who are identified to have lower LVEF should also be evaluated for RVEF.
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二维超声心动图研究糖尿病慢性心力衰竭患者右室射血分数与左室射血分的相关性
糖尿病是最重要的健康问题之一。2型糖尿病(DM)患者更容易患心血管疾病,包括心力衰竭。超声心动图应该有助于早期识别这些心肌异常,这将有助于正确治疗这些个体。该研究进行了18个月,重点关注符合纳入和排除标准的糖尿病和慢性心力衰竭患者。获得了伦理批准,所有患者都同意参与研究。参与者接受了二维超声心动图来评估他们的心脏功能,并记录了相关的实验室检查、成像结果和住院期间接受的药物信息。根据新英国超声心动图学会标准,64例患者左室射血分数(LVEF)受损,31例患者左室射血分数严重受损。大多数LVEF受损的患者(53%)也有右心室射血分数(RVEF)受损。在31例LVEF严重受损的患者中,58%的患者RVEF也严重受损。LVEF与RVEF的相关性有统计学意义(P < 0.05)。LVEF(%)与RVEF(%)呈正相关,差异有统计学意义(P < 0.05)。严重的左心室功能障碍也存在于严重的右心室功能障碍患者中。大多数LVEF降低的患者也有RVEF降低,这种关联是显著的。虽然糖化血红蛋白水平与LVEF和RVEF之间存在相关性,但无统计学意义。因此,对于LVEF较低的患者也应进行RVEF评估。
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51
审稿时长
16 weeks
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