Sneathia infections and adverse perinatal outcomes – short communication

Q4 Immunology and Microbiology Revista Romana de Boli Infectioase Pub Date : 2022-09-30 DOI:10.37897/rjid.2022.3.1
V. Varlas, Vlad Dima, R. Bors
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Abstract

The influence of the maternal vaginal microbiome in vaginal birth is an important factor in the pathogenesis of early-onset neonatal sepsis. The incidence of Sneathia infection is hard to assess due to the difficulty in its detection, as special culture conditions are required. The laboratory methods used in its detection are based on molecular analysis. This emergent, anaerobic agent, by ascending from the female genital tract, can colonize and infect the amniotic fluid, fetal membranes, and placenta. Chorioamnionitis, neonatal sepsis, stillbirth, spontaneous premature labor, and preterm prelabour rupture of the membrane are some of the adverse reactions that can be associated with the presence of Sneathia. In conclusion, Sneathia infection, although underestimated due to its virulence, represents an increased risk of maternal-fetal infections, with the risk of developing a series of neonatal complications. The detection and treatment of this infection will contribute to a decrease in neonatal morbidity and mortality.
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Sneathia感染和不良围产期结果——简短沟通
母体阴道微生物组在阴道分娩中的影响是早发性新生儿败血症发病机制的一个重要因素。由于需要特殊的培养条件,Sneathia感染的发生率很难评估,因为它的检测很困难。用于检测它的实验室方法是基于分子分析的。这种从女性生殖道上升的新兴厌氧剂可以定植并感染羊水、胎膜和胎盘。绒毛膜羊膜炎、新生儿败血症、死产、自发性早产和早产胎膜破裂是可能与Sneathia相关的一些不良反应。总之,尽管由于Sneathia感染的毒力而被低估,但它代表着母婴感染的风险增加,并有发展一系列新生儿并发症的风险。这种感染的检测和治疗将有助于降低新生儿发病率和死亡率。
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CiteScore
0.10
自引率
0.00%
发文量
11
审稿时长
4 weeks
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