Neutrophil to lymphocyte ratio and immature granulocyte: assessing for promising parameters to monitor tuberculosis-diabetes mellitus patients

Abstract

Tuberculosis remains as a major global public health threat and infected more than >10 million cases worldwide. Nowadays, public have witnessed epidemiological shift between chronic and infectious disease globally. Diabetes mellitus as a non-communicable disease and on the other side, Tuberculosis as an infectious disease coexist in the same individual may became health challenge in the near future. DM’s impact on clinical presentation and treatment outcome of TB remains poorly. Detecting and managing TB patients with DM comorbidity by routine laboratory screening provides an opportunity for monitoring patients' prognosis and decreasing disease severity to better outcomes. But in facts, not all laboratory services can provide complex yet expensive assays. Studies has shown Neutrophil to Lymphocyte Ratio (NLR) and Immature Granulocyte Percent (IG%) may be an option as an easy, quick, simple, low-cost, repeatable and reliable assays to monitor TB-DM patient’s prognosis.