A varied presentation of dermal adnexal tumours: An institutional study

IF 0.4 Q4 BIOLOGY Advances in Human Biology Pub Date : 2022-09-01 DOI:10.4103/aihb.aihb_144_21
Snigdha Sinha, Subhashis Das, K. Raju
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Abstract

Introduction: Adnexal skin tumours are a heterogeneous group of uncommon tumours usually misdiagnosed clinically due to a huge variety of types and their variants. Histopathology usually helps in establishing the diagnosis. The study was conducted to analyse the morphological, clinical and histological features of adnexal tumours (ATs) of the skin at our centre over a period of 5 years. Materials and Methods: A retrospective study was conducted over a period of 5 years (January 2016–January 2021), comprising 85 ATs of skin diagnosed in the Department of Pathology, Sri Devaraj URS Medical College, Kolar, Karnataka, India. All the consecutively reported AT cases were reviewed and reclassified as ATs arising from sebaceous glands, hair follicles or sweat glands. The concordance of clinical and histopathological diagnosis was also assessed. Results: Most of the ATs were benign, with the head and neck being the most common location (61.15%), followed by the trunk (22.3%). Nearly 39% of the tumours were of hair follicle differentiation, 30% sweat gland differentiation and sebaceous gland tumours accounted for 31%. The most common varieties of tumours encountered in the present study included sebaceous cysts and pilomatricoma. The concordance between the clinical and histopathological diagnosis was found to be 50% approximately. Conclusion: Histopathology is the gold standard for diagnosing ATs as they are often misdiagnosed clinically.
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真皮附件肿瘤的不同表现:一项机构研究
附件皮肤肿瘤是一组异质性的罕见肿瘤,由于其类型及其变异种类繁多,临床上常被误诊。组织病理学通常有助于确定诊断。本研究旨在分析我们中心5年来皮肤附件肿瘤(ATs)的形态学、临床和组织学特征。材料和方法:回顾性研究为期5年(2016年1月- 2021年1月),包括在印度卡纳塔克邦Kolar的Sri Devaraj URS医学院病理科诊断的85例ATs皮肤。对所有连续报道的AT病例进行回顾,并将其重新分类为皮脂腺、毛囊或汗腺引起的AT。临床和组织病理学诊断的一致性也进行了评估。结果:绝大多数ATs为良性,以头颈部最常见(61.15%),其次为躯干(22.3%)。毛囊分化型肿瘤占39%,汗腺分化型肿瘤占30%,皮脂腺肿瘤占31%。本研究中最常见的肿瘤类型包括皮脂腺囊肿和毛瘤。临床诊断与病理诊断的一致性约为50%。结论:组织病理学是诊断ATs的金标准,临床上极易误诊。
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发文量
37
审稿时长
11 weeks
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