Correlation of Serum Adiponectin with Hepatic Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by excessive triglyceride accumulation in the hepatocytes. It is a hepatic manifestation of metabolic syndrome [1]. The prevalence of NAFLD in India above 20 years age was 18.9% [2]. The prevalence of NAFLD increased with increased age. Obesity, diabetes mellitus (DM), insulin resistance (IR) are predisposing factors for NAFLD. Although NAFLD is more common in subject with obesity and diabetes mellitus (DM), it also occurs in lean and non-diabetic subject [3,4,5]. Non obese was 25.6% among NAFLD patient in Bangladesh. About 53.1 % of non-obese NAFLD cases were NASH [6].