Cover Image: Salmonella Typhimurium manipulates macrophage cholesterol homeostasis through the SseJ-mediated suppression of the host cholesterol transport protein ABCA1 (Cellular Microbiology 08/2021)

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2021-07-13 DOI:10.1111/cmi.13377
Adam R. Greene, Katherine A. Owen, James E. Casanova
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Abstract

Salmonella Typhimurium induces accumulation of cholesterol in WT macrophages (top right) but not in the absence of the host kinase FAK (bottom left) or the bacterial effector protein SseJ (bottom right). For further details, readers are referred to the article by Greene et al. on p. e13329 of this issue.

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封面图片:鼠伤寒沙门氏菌通过SseJ介导的对宿主胆固醇转运蛋白ABCA1的抑制来操纵巨噬细胞胆固醇稳态(细胞微生物学,2021年8月)
鼠伤寒沙门氏菌在WT巨噬细胞中诱导胆固醇积累(右上),但在缺乏宿主激酶FAK(左下)或细菌效应蛋白SseJ(右下)的情况下不会。欲了解更多细节,请参阅本期e13329页Greene等人的文章。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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