GROUP B STREPTOCOCCAL INFECTIONS DURING PREGNANCY AND PERINATAL CONSEQUENCES: WHAT DO WE NEED TO DETERMINE MORE THAN A BACTERIOLOGICAL ANALYSIS?

Q4 Immunology and Microbiology Revista Romana de Boli Infectioase Pub Date : 2021-06-30 DOI:10.37897/rjid.2021.2.2
A. Simionescu, B. Pharmacy, A. Stănescu
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引用次数: 1

Abstract

Group B of streptococcal infection is responsible for maternal and fetal morbidity and mortality. Fetal consequences of streptococcal B infection may lead to puerperal sepsis, meningitis, encephalitis or pneumonia. Long-term consequences may determine neurological sequelae and mental disabilities, and very rare are reported cases for the late death of the child. Maternal consequences of streptococcal B infection are endometritis and sepsis. Universal screening and antibioprophylaxy during labour are safe and effective. But, systematic intrapartum prophylaxis for carriers of SGB does not appear to have effects on long-term complications. Also, systematic cultures in neonates do not appear to detect antenatally all carriers of streptococcus B. Herein, we present the particularity of streptococcal infection in pregnancy that may contribute to further strategy. Better laboratory tests for identifying serotypes, genotypes and phenotypes must be available, significantly to differentiate between dtreptococcal high- and low-risk regarding materno-fetal consequences.Immunization remains a promising way to eradicate this infection.
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妊娠期B组链球菌感染和围产期后果:除了细菌分析,我们还需要确定什么?
链球菌感染的B组是孕产妇和胎儿发病率和死亡率的原因。链球菌B感染的胎儿后果可能导致产褥期败血症、脑膜炎、脑炎或肺炎。长期后果可能决定神经后遗症和精神残疾,据报道,儿童晚期死亡的病例非常罕见。链球菌B感染的母体后果是子宫内膜炎和败血症。分娩期间进行全面筛查和抗微生物预防是安全有效的。但是,对SGB携带者进行系统的产时预防似乎对长期并发症没有影响。此外,新生儿的系统培养似乎并不能在产前检测到所有的B型链球菌携带者。在此,我们介绍了妊娠期链球菌感染的特殊性,这可能有助于进一步的策略。必须提供更好的实验室测试来识别血清型、基因型和表型,以显著区分双球菌对母胎后果的高风险和低风险。免疫接种仍然是根除这种感染的一种有希望的方法。
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CiteScore
0.10
自引率
0.00%
发文量
11
审稿时长
4 weeks
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