Quantitative microbial risk assessment for Escherichia coli O157:H7 in Mutton in Qatar: an example of application of One Health approach

Abstract

The objectives of the study were to evaluate the risk of illness from the consumption of Mutton contaminated with Escherichia coli O157:H7 in Qatar and to highlight intervention points that would contribute to mitigating its associated risk. The quantitative risk assessment (QRA) methodology was employed to address this objective. Our approach consisted of a combination of deterministic and stochastic approaches. Data on the probability of E. coli O157:H7 in animals, animal products, retail, and humans were obtained through repeat cross-sectional studies. Estimates of the adverse health effects were computed using risk characterization which integrated data on hazard characterization and exposure assessment, including dose-response models. The probability of illness for a healthy female from the consumption of mutton contaminated with E. coli O157:H7 eating at a restaurant ranged from 7×10-3 to 28×10-2 depending on the amount of food consumed. However, the risk for the same female eating at home is less (5×10-3 to 24×10-2). The estimates of illness are three times higher for immunocompromised females exposed either at a restaurant or at home. The risk of illness due to this pathogen could be significantly reduced for either gender under different scenarios by increasing the efficacy of roasting the mutton before consumption.