Combined Treatment of Vildagliptin/Metformin (Equmet) and Imeglimin (Twymeeg) with Clinical Efficacy

H. Bando, H. Yamashita, Y. Kato, K. Ogura, Y. Kato
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引用次数: 4

Abstract

Background: Vildagliptin/Metformin (EquMet) and imeglimin (Twymeeg) are effective oral hypoglycemic agents (OHAs) for patients with type 2 diabetes (T2D). Case Presentation: The patient was a 68-year-old male with T2D and fatty liver for several years. In November 2022, his HbA1c had increased to 8.2%, and he was started on Twymeeg, followed by EquMet. Results: Over the course of four months, the patient’s HbA1c value successfully decreased from 8.2% to 6.7%, and he did not experience any gastrointestinal adverse effects (GIAEs). Discussion and Conclusion: The combined treatment of EquMet and Twymeeg demonstrated clinical efficacy without any adverse effects. The Trials of IMeglimin for Efficacy and Safety (TIMES) provided various evidence of imeglimin’s effectiveness.
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维格列汀/二甲双胍(Equmet)与依米明(Twymeeg)联合治疗临床疗效观察
背景:维格列汀/二甲双胍(EquMet)和伊美米明(Twymeeg)是治疗2型糖尿病(T2D)的有效口服降糖药(OHAs)。病例介绍:患者为男性,68岁,t2dm合并脂肪肝多年。2022年11月,他的糖化血红蛋白上升到8.2%,开始服用Twymeeg,随后服用EquMet。结果:在4个月的治疗过程中,患者的HbA1c值成功地从8.2%降至6.7%,且未出现任何胃肠道不良反应(giae)。讨论与结论:EquMet与Twymeeg联合治疗临床疗效良好,无不良反应。伊美美明的疗效和安全性试验(TIMES)提供了伊美美明有效性的各种证据。
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