Traditional Chinese Medicine syndrome elements of male infertility revealed by latent tree model analysis

IF 2 4区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Journal of Traditional Chinese Medicine Pub Date : 2018-12-15 DOI:10.1016/S0254-6272(18)30993-2

Zhang Zhijie , Liu Shaoming , Zhang Yueyang , Yang Jingzhe , Kong Tao , Wang Chengli , Ning Peng , Chen Xiaochao , Li Xuesong , Jia Yusen , Chen Xiaojun

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引用次数: 8

Abstract

OBJECTIVE

To explore the features of Traditional Chinese Medicine (TCM) syndromes in male infertility using computer-based analyses.

METHODS

Latent class analysis was used to analyze the TCM syndrome data from 813 patients with male infertility and establish a latent tree model.

RESULTS

A latent tree model with a Bayesian information criterion score of – 11 263 was created. This model revealed that the characteristics of basic TCM syndromes in patients with male infertility were kidney Yang deficiency, kidney Qi deficiency, spleen Yang deficiency, liver Qi stagnation, Qi stagnation and blood stasis, and dump-heat; moreover, most patients with male infertility had complex syndromes (spleen-kidney Yang deficiency and liver Qi stagnation) rather than simple single syndromes.

CONCLUSION

The hidden tree model analysis revealed the objective and quantitative complex relationships between the TCM symptoms of male infertility, and obtained the quantification and objective evidence of TCM syndromes in male infertility.

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潜在树模型分析揭示男性不育症的中医证候要素

目的利用计算机分析方法探讨男性不育症中医证候特征。方法采用潜类分析方法，对813例男性不育症中医证候资料进行分析，建立潜树模型。结果建立了贝叶斯信息准则得分为- 11 263的sa潜树模型。该模型揭示了男性不育症患者的基本中医证候特征为肾阳虚、肾气虚、脾阳虚、肝郁、气滞血瘀、郁热;而且，男性不育症患者大多有脾肾阳虚、肝郁等复合证型，而不是单纯的单一证型。结论隐含树模型分析揭示了男性不育症中医证候之间客观与定量的复杂关系，获得了男性不育症中医证候的定量化和客观证据。

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来源期刊

Journal of Traditional Chinese Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

2.40

自引率

3.80%

发文量

32269

审稿时长

2 months

期刊介绍： Journal of Traditional Chinese Medicine（JTCM） is devoted to clinical and theortical research on the use of acupuncture and Oriental medicine. The main columns include Clinical Observations, Basic Investigations, Reviews, Questions and Answers, an Expert''s Forum, and Discussions of Clinical Cases. Its key topics include acupuncture and electro-acupuncture, herbal medicine, homeopathy, masseotherapy, mind-body therapies, palliative care, and other CAM therapies.