Cicatrização de feridas crónicas tratadas com oleorresina de copaíba

Abstract

Background: Chronic wounds represent a growing health problem in several countries. Ethnobo-tanical and preclinical studies suggest that copaiba oleoresin ( Copaifera sp.) has healing properties. Objective: To evaluate the clinical application of copaiba oleoresin in chronic wound healing. Methodology: Retrospective case series study consisting of 6 participants with chronic wounds treated with 7% copaiba oleoresin with sunflower oil or 10% copaiba ointment. The primary endpoint was the percentage reduction in wound area at the end of follow-up. Results: Mean age of participants was 54.5 ( SD = 11.5) years. The causes of wounds were vascular ( n = 3), surgical ( n = 2), and traumatic ( n = 1). All participants had a reduction of the wound area ranging from 15.5% to 100% during the follow-up (8 to 15 weeks). No complications were observed. Conclusion: Treatment with copaiba oleoresin proved to be an effective and safe option in chronic wound treatment.