Exploring Treatment Options for Eosinophilic Esophagitis

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY Gastroenterology Insights Pub Date : 2022-07-14 DOI:10.3390/gastroent13030023
N. Strossman, K. Donovan, Alex Trovato, Nihita Manem, Nicole Nudelman, Micheal Tadros, C. Ashley
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引用次数: 1

Abstract

Eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus, has been increasing in incidence over the past several years. Mainstays of treatment include dietary modifications, steroids, proton pump inhibitors (PPIs), and endoscopic dilation, with the goal being to control disease progression, promote remission, and alleviate symptoms, such as dysphagia and food impaction. In addition to these well-known treatment options, preliminary studies on new medications that target specific inflammatory mediators involved in the pathogenesis of EoE have shown promise in improving symptoms. This review article summarizes and discusses the application and efficacy of long-standing and promising new treatment options for EoE.
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嗜酸性食管炎治疗方案探讨
嗜酸性食管炎(EoE)是一种食道的慢性炎症性疾病,在过去几年中发病率一直在增加。治疗的主要手段包括饮食调整、类固醇、质子泵抑制剂(PPIs)和内镜扩张,目的是控制疾病进展、促进病情缓解和缓解症状,如吞咽困难和食物嵌塞。除了这些众所周知的治疗方案外,针对参与EoE发病机制的特定炎症介质的新药的初步研究表明,有希望改善症状。这篇综述文章总结并讨论了长期存在且有前景的EoE新治疗方案的应用和疗效。
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来源期刊
Gastroenterology Insights
Gastroenterology Insights GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
2.80
自引率
3.40%
发文量
35
审稿时长
10 weeks
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