Analysis of Gastric Diseases and Their Symptoms Based on Indexes of Pepsinogen I (PGI) and Pepsinogen II (PGII): Take 1106 Patients as Samples

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2022-05-17 DOI:10.1155/2022/8393351
Kuan-peng Guo, Zhengqiu Li, Bibo Qiu, Bin Hu, Suwu Yi
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Abstract

In this study, preoperative analysis of 1106 gastropathy patients with abdominal pain, vomiting, dyspepsia, and other symptoms was conducted. Independent sample t -test and correlation analysis and other ways were used for data cleansing and analysis. Findings were as follows: (1) Samples of different genders showed significance in PGI and PGII. The PGI and PGII values of women were significantly lower than those of men. (2) Age showed a significant positive correlation with PGI and PGII, which indicates that as the age increases, the PGI and PGII values become higher. (3) There was a significant negative correlation between age and abdominal pain. This signified that the younger the patient is, the more likely they will suffer abdominal pain. (4) PGI displayed a positive correlation with abdominal pain in the digestive tract (dyspepsia, gastrointestinal ulcers, gastrointestinal bleeding, etc.). It indicated that the higher the PGI value is, the more likely the patients will suffer abdominal pain and gastrointestinal diseases (dyspepsia, gastrointestinal ulcer, gastrointestinal hemorrhage, etc.). (5) PGII displayed a significant positive correlation with gastrointestinal diseases (dyspepsia, gastrointestinal ulcer, gastrointestinal hemorrhage, etc.) and a negative correlation with gastropathy (acute gastritis, chronic superficial gastritis, gastric ulcer, etc.). It indicated that the higher the value of PGII is, the more likely the patients will suffer symptoms of gastrointestinal diseases (dyspepsia, gastrointestinal ulcer, gastrointestinal hemorrhage, etc.), while less likely the patients will suffer gastropathy (acute gastritis, chronic superficial gastritis, gastric ulcer, etc.).
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基于胃蛋白酶原I和蛋白酶原II指标的胃病及其症状分析——以1106例患者为例
本研究对1106例伴有腹痛、呕吐、消化不良等症状的胃病患者进行了术前分析。采用独立样本t检验和相关分析等方法进行数据清理和分析。研究结果如下:(1)不同性别的样本在PGI和PGII中表现出显著性差异。女性的PGI和PGII值明显低于男性。(2) 年龄与PGI和PGII呈显著正相关,表明随着年龄的增加,PGI和PGII值变高。(3) 年龄与腹痛呈显著负相关。这意味着患者越年轻,他们患腹痛的可能性就越大。(4) PGI与消化道腹痛(消化不良、胃肠道溃疡、胃肠道出血等)呈正相关,表明PGI值越高,PGII与胃肠道疾病(消化不良、消化道溃疡、消化道出血等)呈显著正相关,与胃病呈负相关(急性胃炎、慢性浅表性胃炎、胃溃疡等)。表明PGII值越高,患者越有可能出现胃肠道疾病症状(消化不良、胃肠道溃疡、胃肠道出血等),而患者患胃病的可能性越小(急性胃炎,慢性浅表表性胃炎,胃溃疡等等)。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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