Treatment and Research Progress of Articular cartilage injury in HT3SS

Abstract

Objective Articular cartilage injury is one of the most common orthopedic diseases with high morbidity and morbidity, especially in the elderly.Articular cartilage injury causes degenerative changes of articular cartilage, such as osteoarthritis, which can lead to disability, pain during joint movement and deformation of bone and joint.The prevalence of osteoarthritis accounts for 10% ~12% of the total population in the world.It is a common disease.The prevalence of osteoarthritis has increased to 49.7% for the elderly aged over 65 years old (Statistics of the World Health Organization (who) in 2010 show that with the development of social aging and obesity and other adverse factors, these figures will continue to rise.It is known that osteoarthritis is related to aging, trauma, genetic susceptibility, obesity and inflammation, but the specific cause of osteoarthritis has not been fully identified, which leads to many obstacles in clinical treatment of osteoarthritis.At present, most of the clinical and research work in this field is focused on the restoration of cartilage trauma.In this review, we summarize and discuss the methods of cartilage defect repair, as well as the hot spots and directions of future research work. Key words: Cartilage injury; Articular cartilage defects; Osteoarthritis; Therapy