Histoid leprosy, an unusual variant of leprosy - review of literature

Abstract

Histoid leprosy is a rare variant of leprosy with distinctive immunological, clinical, microbiological, and histological characteristics first described by Wade in the year 1963. This is usually reported following dapsone monotherapy, irregular or improper therapy, and rarely de novo. Early diagnosis and treatment of histoid is important as it might serve as a reservoir and source of community spread of leprosy. In this article, we highlight the important aspects of clinical manifestations, immunological, histological, bacteriological, and management aspects of histoid leprosy.