Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications

A. Dagra, E. Williams, S. Aghili-Mehrizi, Michael Goutnik, Melanie B. Martinez, R. Turner, B. Lucke-Wold
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引用次数: 2

Abstract

Rupture of an aneurysm is the leading cause of subarachnoid hemorrhage (SAH) which results in accumulation of blood between the arachnoid and pia mater, consequently increasing intracranial pressure. This often results in life threatening conditions like herniation or clinical presentations including focal neurological deficits. In children, these events, although rare, have significant implications. Pediatric SAH is associated with better outcomes in the hospital setting and may even be prevented proactively by the recognition of potential risk factors. Specifically, better recognition of genetic predispositions, metastatic lesions, and infectious causes of aneurysms is important to understand their growth and prevent hemorrhagic events. This review highlights the causes of pediatric SAH, reviews the models of current understanding of this etiology, and discusses the current treatment schema to provide a succinct summary and highlight gaps in current knowledge. This may lead to future investigations aimed at further improving prevention strategies, patient care, and patient outcomes.
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小儿蛛网膜下腔出血:具有重要意义的罕见事件
动脉瘤破裂是蛛网膜下腔出血(SAH)的主要原因,SAH会导致蛛网膜和软脑膜之间的血液积聚,从而增加颅内压。这通常会导致危及生命的情况,如疝或临床表现,包括局灶性神经功能缺损。在儿童中,这些事件虽然罕见,但具有重要意义。儿科SAH在医院环境中与更好的结果相关,甚至可以通过识别潜在的风险因素来预防。具体来说,更好地认识动脉瘤的遗传易感性、转移性病变和感染原因对于了解其生长和预防出血事件很重要。这篇综述强调了儿科SAH的原因,回顾了目前对该病因的理解模式,并讨论了目前的治疗方案,以提供简洁的总结并强调当前知识的差距。这可能会导致未来的调查,旨在进一步改进预防策略、患者护理和患者结果。
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