Monleypox virus a rising concern in current age: A Mini Review on Epedmilogy, Clinical menifestations and Therapeutic interventions

Irsa Shabbir, A. Qader, Z. Ahmad, H. Tariq, M. Davis, Sadia Rafique, Ali Zia
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Abstract

The aim of our study is to enhance the awareness about monkeypox virus among people so that its drastic effects can be overcome easily. An orthopox virus of the poxviridae family called the monkeypox virus (MPV) is currently causing worry on a global scale. It has two recognized viral clades and is indigenous to central and western Africa. The natural reservoirs are probably a variety of African rodents and primates. Direct contact with diseased animals, such as bites, scratches, and butchering, results in zoonotic transmission. Human to human transmission happens when two people come into close touch (for example, through skin-to-skin contact, sexual contact, or respiratory droplets). Human MPV illness often starts with a fever prodrome and lymphadenopathy,and then progresses to a diffuse maculopapular to vesiculopustular skin/mucosal lesion eruption. The febrile prodrome may be lacking in the current 2022 outbreak, which is mostly affecting males who have sex with men (MSM), and skin/mucosal lesions. The data in this study was collected from different data basis like google scholar, pubmed and medline etc by using various key words. However, the existing data is clearly indicating the drastic impact of MPV on human health and necessay steps must be taken to overcome it.
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猴痘病毒在当今时代日益受到关注:流行病学、临床表现和治疗干预措施综述
本研究的目的是提高人们对猴痘病毒的认识,以便容易地克服猴痘病毒的严重影响。猴痘病毒(MPV)是痘病毒科的一种正痘病毒,目前正在全球范围内引起担忧。它有两个公认的病毒分支,原产于中非和西非。自然宿主可能是各种非洲啮齿动物和灵长类动物。与患病动物的直接接触,如咬伤、抓伤和屠宰,可导致人畜共患疾病传播。人与人之间的传播发生在两个人密切接触时(例如,通过皮肤接触、性接触或呼吸道飞沫)。人类MPV疾病通常以发热前驱症状和淋巴结病变开始,然后发展为弥漫性丘疹或水泡样皮肤/粘膜病变。目前的2022年暴发可能缺乏发热前驱症状,这主要影响男男性行为者(MSM)和皮肤/粘膜病变。本研究的数据来源于谷歌scholar、pubmed、medline等不同的数据库,使用不同的关键词。然而,现有数据清楚地表明MPV对人类健康的严重影响,必须采取必要的步骤来克服它。
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