Clinical value of peroral endoscopic cardial constriction for gastroesophageal reflux disease

中华消化内镜杂志 Pub Date : 2019-08-20 DOI:10.3760/CMA.J.ISSN.1007-5232.2019.08.005

Hai-qing Hu, Haijing Zhang, Chunlu Jin

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Abstract

Objective To study the safety and efficacy of peroral endoscopic cardial constriction (PECC) for gastroesophageal reflux disease (GERD). Methods A total of 27 patients with GERD who visited the Affiliated Hospital of Inner Mongolia Medical University from August 2016 to December 2017 and met the inclusion criteria received PECC. The 24 h esophageal pH-resistance monitoring (DeMeester) scores, GERD health-related quality of life (GERD-HRQL) scores, GERD-questionnaires (GERD-Q) symptom scores and clinical efficacy before and after operation were compared. Results DeMeester score at 3 months (Z=-6.940, P=0.001) and 6 months (Z=-6.307, P=0.001) after treatment, GERD-HRQL score at 3 months (t=11.499, P=0.001) and 6 months (t=10.959, P=0.001) as well as GERD-Q symptom score at 3 months (t=30.647, P=0.001) and 6 months (t=27.217, P =0.001) after surgery significantly decreased, compared with those before. The curative rates were 81.5% (22/27) and 77.8% (21/27) at 3 months and 6 months after operation. Conclusion PECC, a new method for the treatment of GERD with good short-term effect, safety and feasibility, can be recommended for clinical application. Key words: Cardia; Gastroesophageal reflux; Efficiency; Safety; Peroral endoscopic cardial constriction

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经口内镜心脏缩窄术治疗胃食管反流病的临床价值

目的探讨经口内镜下贲门狭窄（PECC）治疗胃食管反流病（GERD）的安全性和有效性。方法对2016年8月至2017年12月在内蒙古医科大学附属医院就诊并符合纳入标准的27例GERD患者进行PECC检查。比较术前和术后24小时食管pH抵抗监测（DeMeester）评分、胃食管反流病健康相关生活质量（GERD-HRQL）评分、GERD问卷（GERD-Q）症状评分和临床疗效。结果治疗后3个月（Z=6.940，P=0.001）和6个月（Z=6.307，P=0.001。术后3个月和6个月的治愈率分别为81.5%（22/27）和77.8%（21/27）。结论PECC是一种治疗GERD的新方法，短期疗效好，安全可行，值得临床推广应用。关键词：卡迪亚；胃食管反流；效率；安全；经口内镜下心脏收缩

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来源期刊

中华消化内镜杂志

CiteScore

0.10

自引率

0.00%

发文量

7555

期刊介绍： Chinese Journal of Digestive Endoscopy is a high-level medical academic journal specializing in digestive endoscopy, which was renamed Chinese Journal of Digestive Endoscopy in August 1996 from Endoscopy. Chinese Journal of Digestive Endoscopy mainly reports the leading scientific research results of esophagoscopy, gastroscopy, duodenoscopy, choledochoscopy, laparoscopy, colorectoscopy, small enteroscopy, sigmoidoscopy, etc. and the progress of their equipments and technologies at home and abroad, as well as the clinical diagnosis and treatment experience. The main columns are: treatises, abstracts of treatises, clinical reports, technical exchanges, special case reports and endoscopic complications. The target readers are digestive system diseases and digestive endoscopy workers who are engaged in medical treatment, teaching and scientific research. Chinese Journal of Digestive Endoscopy has been indexed by ISTIC, PKU, CSAD, WPRIM.