A Patient Diagnosed with POEMS Syndrome with Atypical Presentation: A Case Report

H. Semiz, Roxana Carmen Geana, D. Sorostinean, Iliescu Va, A. Drăgan
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Abstract

POEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis.
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一位被诊断为POEMS综合征的非典型患者:一例报告
POEMS综合征是一种由潜在浆细胞肿瘤引起的副肿瘤综合征。该综合征的主要标准是多神经根性神经病、克隆性浆细胞病(PCD)、骨硬化病变、血管内皮生长因子升高以及是否存在Castleman病。次要特征包括器官肥大、内分泌疾病、特征性皮肤变化、视乳头水肿、血管外容量超负荷和血小板增多症。
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