Characterization and Extraction of Bioactive Compounds in Ethanolic Extract of Moringa concanensis, Nimmo Leaf, Using Microwave-assisted and Soxhlet Techniques
Amerendra Singh, Santoshkumar Singh, P. Upadhyay, J. Mishra, V. Vishwakarma
{"title":"Characterization and Extraction of Bioactive Compounds in Ethanolic Extract of Moringa concanensis, Nimmo Leaf, Using Microwave-assisted and Soxhlet Techniques","authors":"Amerendra Singh, Santoshkumar Singh, P. Upadhyay, J. Mishra, V. Vishwakarma","doi":"10.2174/1574885518666230522122556","DOIUrl":null,"url":null,"abstract":"\n\nThe extraction of Moringa concanensis (Nimmo leaf) was done in ethanol using Soxhlet and microwave-assisted extraction (MAE) techniques to obtain bioactive compounds.\n\n\n\nThe standard techniques were used to carry out phytochemical analysis of ethanolic extract. The analysis confirmed the presence of flavonoids, phenols, steroids, alkaloids, terpenoids, glycosides, tannins, and saponins, and also the absence of anthraquinones. Moreover, the extract was evaluated for antioxidant activities using DPPH and ABTS assays. The IC50 value of the extract was also determined.\n\n\n\nA clear correlation between the total phenolic content, total flavonoid content, and antioxidant activity of the leaf extracts was obtained.\n\n\n\nConclusion: This study suggests that a high amount of phenolic compounds could be obtained from Moringa concanensis (Nimmo leaf) by using the microwave-assisted extraction technique, which may be responsible for its antioxidant activity.\n","PeriodicalId":11004,"journal":{"name":"Current Drug Therapy","volume":" ","pages":""},"PeriodicalIF":0.3000,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Drug Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1574885518666230522122556","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
The extraction of Moringa concanensis (Nimmo leaf) was done in ethanol using Soxhlet and microwave-assisted extraction (MAE) techniques to obtain bioactive compounds.
The standard techniques were used to carry out phytochemical analysis of ethanolic extract. The analysis confirmed the presence of flavonoids, phenols, steroids, alkaloids, terpenoids, glycosides, tannins, and saponins, and also the absence of anthraquinones. Moreover, the extract was evaluated for antioxidant activities using DPPH and ABTS assays. The IC50 value of the extract was also determined.
A clear correlation between the total phenolic content, total flavonoid content, and antioxidant activity of the leaf extracts was obtained.
Conclusion: This study suggests that a high amount of phenolic compounds could be obtained from Moringa concanensis (Nimmo leaf) by using the microwave-assisted extraction technique, which may be responsible for its antioxidant activity.
期刊介绍：
Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
