"Albuminuria in the Elderly More than a Marker of Renal or Cardiovascular Disease"

J. Barzilay
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Abstract

Albuminuria the presence of more than 30 mg of alumin per one gram of creatinine in the urine is highly prevalent in older adults. Based on data from the NHANES III study, more than 20% of adults over the age of 70 years have albuminuria, while among similarly aged adults with diabetes the prevalence reaches 40% [1,2]. To date, most studies have examined albuminuria as a risk factor for cardiovascular disease. We too have found albuminuria to be associated with a 70-80% increased prevalence of cardiovascular disease [3] and a doubling of mortality risk (mostly cardiovascular in nature) [4] as compared to older people without microalbuminuria.
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老年人蛋白尿不仅仅是肾脏或心血管疾病的标志
白蛋白尿——尿中每克肌酸酐中存在超过30毫克的明矾,在老年人中非常普遍。根据NHANES III研究的数据,超过20%的70岁以上的成年人患有蛋白尿,而在同样年龄的糖尿病成年人中,患病率达到40%[1,2]。迄今为止,大多数研究都将蛋白尿作为心血管疾病的危险因素。我们也发现,与没有微量白蛋白尿的老年人相比,白蛋白尿与心血管疾病患病率增加70-80%有关[3],死亡率增加一倍(主要是心血管疾病)[4]。
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