Efficacy of amaranth grain consumption on CD4 count and morbidity patterns among adults living with HIV in Nyeri, Kenya

Z. Ndungu, E. Kuria, N. Gikonyo, D. Mbithe
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引用次数: 3

Abstract

Human immunodeficiency virus (HIV) is associated with increased nutrient needs and compromised body immunity. Minimal information exists on effect of food-based interventions on health status of people living with HIV (PLHIV) and not on antiretroviral therapy (ART). This study investigated the efficacy of amaranth grain (Amaranthus cruentus) consumption on CD4 count and morbidity patterns among PLHIV. A one group pre-test-post-test study design was used on a sample of 66 pre-ART adults living with HIV. The study involved collection of baseline characteristics of the respondents; this was followed by consumption of amaranth grain porridge (100 g) for six months. Post-test data was collected and paired t- test was used to compare pre-test and post-test data. Daily consumption of 100 g of amaranth grain porridge increased nutrient intake. A significant increase (P=0.004) in CD4 count from 498.2±163 SD at baseline to 608 ± 157 SD post-test was observed. There was a significant decline in the number of respondents with any form of illnesses from a total of 52 (78.8%) at baseline to 21 (31.8%) respondents at month six (P=0.031). Amaranth grain increased nutrient intake, CD4 count and consequently reduced the prevalence of illness. The study recommends that nutrition and health practitioners should educate PLHIV on importance of use of amaranth grain to complement usual dietary intake. Key words: Amaranth grain, CD4 count, morbidity pattern, people living with human immunodeficiency virus (PLHIV).
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在肯尼亚尼耶里,苋菜谷物消费对艾滋病毒感染者CD4计数和发病率模式的影响
人体免疫缺陷病毒(HIV)与营养需求增加和身体免疫力受损有关。关于基于食物的干预措施对艾滋病毒感染者健康状况的影响,而不是对抗逆转录病毒疗法的影响,信息很少。本研究调查了食用苋粒对PLHIV患者CD4计数和发病模式的影响。一组试验前试验后研究设计用于66名艾滋病病毒携带者的ART前成人样本。该研究涉及收集受访者的基线特征;随后食用苋粒粥(100g)6个月。收集测试后数据,并使用配对t检验来比较测试前和测试后的数据。每天食用100克的苋粒粥可以增加营养素的摄入。观察到CD4计数从基线时的498.2±163 SD显著增加(P=0.004)到测试后的608±157 SD。患有任何形式疾病的受访者数量显著下降,从基线时的52人(78.8%)下降到第六个月时的21人(31.8%)(P=0.031)。苋粒增加了营养摄入和CD4计数,从而降低了疾病的患病率。该研究建议营养和健康从业者应教育PLHIV使用苋粒补充日常饮食摄入的重要性。关键词:苋粒,CD4计数,发病模式,人类免疫缺陷病毒(PLHIV)感染者。
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