Evaluation of neoadjuvant therapy for pancreatic cancer: is it the best choice?

Yinmo Yang
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Abstract

Currently the treatment strategy of pancreatic cancer has shifted from the mode "surgery first" to multidisciplinary team. More and more evidences have revealed that neoadjuvant therapy will help to increase the R0 resection rate, reduce the recurrence rate, and improve the prognosis of the patients with borderline resectable pancreatic cancer. Furthermore, neoadjuvant therapy is also recommended for resectable pancreatic cancer patients with high risk factors of tumor recurrence. In this article, the current controversy and research progress of neoadjuvant therapy for pancreatic cancer are reviewed and commented in order to deepen the understanding of the hot topic in clinial surgeons. Key words: Pancreatic neoplasms; Resectablity; Neoadjuvant therapy; Multidisciplinary team; Efficacy
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癌症新辅助治疗的评价:它是最佳选择吗?
目前癌症的治疗策略已从“手术为主”的模式转变为多学科团队治疗。越来越多的证据表明,新辅助治疗有助于提高可边缘切除的癌症患者的R0切除率,降低复发率,改善预后。此外,对于肿瘤复发危险因素高的可切除癌症患者,也推荐新辅助治疗。本文就目前癌症新辅助治疗的争议和研究进展进行了综述和评述,以加深临床对这一热点问题的认识。关键词:胰腺肿瘤;怨恨;新辅助治疗;多学科团队;功效
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中华消化外科杂志
中华消化外科杂志 Medicine-Gastroenterology
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