{"title":"Comparative estimation of proteinuria using spot urine albumin creatinine ratio and 24 hour urine protein among diabetics for detecting nephropathy","authors":"S. Afzalpurkar, V. Deokar","doi":"10.18137/cardiometry.2023.26.285292","DOIUrl":null,"url":null,"abstract":"Purpose: Although proteinuria has been established as an independent risk factor of diabetic nephropathy, the timely and accurate estimation of proteinuria has scope for improvement. Hence, this study intends to compare the accuracy of spot sampled urine albumin creatinine ratio (UACR) to 24 hour urine protein among diabetics in the quantification of proteinuria. Design/Methodology/Approach: This prospective study was conducted amongst 120 patients diagnosed with type 2 diabetes mellitus. Two types of urine samples namely spot samples and 24-hour samples were analysed across an array of clinical variables including urine biochemistry, kidney failure and glomerular filtration rate. UACR in spot samples was correlated with the 24-hour urine protein levels. The sensitivity, accuracy, specificity and predictive values of UACR for proteinuria were determined. A p","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiometry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18137/cardiometry.2023.26.285292","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: Although proteinuria has been established as an independent risk factor of diabetic nephropathy, the timely and accurate estimation of proteinuria has scope for improvement. Hence, this study intends to compare the accuracy of spot sampled urine albumin creatinine ratio (UACR) to 24 hour urine protein among diabetics in the quantification of proteinuria. Design/Methodology/Approach: This prospective study was conducted amongst 120 patients diagnosed with type 2 diabetes mellitus. Two types of urine samples namely spot samples and 24-hour samples were analysed across an array of clinical variables including urine biochemistry, kidney failure and glomerular filtration rate. UACR in spot samples was correlated with the 24-hour urine protein levels. The sensitivity, accuracy, specificity and predictive values of UACR for proteinuria were determined. A p
目的：尽管蛋白尿已被确定为糖尿病肾病的独立危险因素，但及时准确地估计蛋白尿仍有改进的余地。因此，本研究旨在比较糖尿病患者尿白蛋白-肌酐比值（UACR）与24小时尿蛋白定量的准确性。设计/方法/方法：这项前瞻性研究在120名被诊断为2型糖尿病的患者中进行。分析了两种类型的尿液样本，即现场样本和24小时样本，涉及一系列临床变量，包括尿液生物化学、肾衰竭和肾小球滤过率。点样本中的UACR和24小时尿蛋白水平相关。测定UACR对蛋白尿的敏感性、准确性、特异性和预测值。A p
期刊介绍：
Cardiometry is an open access biannual electronic journal founded in 2012. It refers to medicine, particularly to cardiology, as well as oncocardiology and allied science of biophysics and medical equipment engineering. We publish mainly high quality original articles, reports, case reports, reviews and lectures in the field of the theory of cardiovascular system functioning, principles of cardiometry, its diagnostic methods, cardiovascular system therapy from the aspect of cardiometry, system and particular approaches to maintaining health, engineering peculiarities in cardiometry developing. The interdisciplinary areas of the journal are: hemodynamics, biophysics, biochemistry, metrology. The target audience of our Journal covers healthcare providers including cardiologists and general practitioners, bioengineers, biophysics, medical equipment, especially cardiology diagnostics device, developers, educators, nurses, healthcare decision-makers, people with cardiovascular diseases, cardiology and engineering universities and schools, state and private clinics. Cardiometry is aimed to provide a wide forum for exchange of information and public discussion on above scientific issues for the mentioned experts.
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