Kelly de Freitas Santos , Ieda Aparecida Diniz , Nayara Ragi Baldoni , Márcia Christina Caetano Romano , Joel Alves Lamounier
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引用次数: 0
Abstract
The intestinal microbiota has been shown to be a potential determining factor in the development of obesity. The aim of this systematic review was to identify the effect of probiotic supplementation in children with obesity. Randomized Clinical Trials (RCTs) of interventions with the oral use of probiotics for children with obesity were considered eligible. The PubMed, Scopus, Science Direct, Web of Science, VHL, and Embase databases were used as a source of information. The risk of bias was assessed using the Cochrane Risk of bias criteria. Most of the articles included were carried out in developed countries and showed the benefits of probiotic intervention in reducing anthropometric indices in children with obesity. Future RCTs are needed to assess the effect of probiotics in the absence of weight loss strategies, in order to truly ascertain the specific benefits of probiotic strains on adiposity.
肠道微生物群已被证明是肥胖发展的潜在决定因素。本系统综述的目的是确定益生菌补充剂对肥胖儿童的影响。口服益生菌干预肥胖儿童的随机临床试验(rct)被认为是合格的。使用PubMed、Scopus、Science Direct、Web of Science、VHL和Embase数据库作为信息来源。采用Cochrane偏倚风险标准评估偏倚风险。大多数纳入的文章都是在发达国家进行的，并显示了益生菌干预在降低肥胖儿童的人体测量指数方面的益处。未来的随机对照试验需要在没有减肥策略的情况下评估益生菌的效果，以真正确定益生菌菌株对肥胖的具体益处。
Obesity MedicineMedicine-Public Health, Environmental and Occupational Health
CiteScore
5.50
自引率
0.00%
发文量
74
审稿时长
40 days
期刊介绍：
The official journal of the Shanghai Diabetes Institute Obesity is a disease of increasing global prevalence with serious effects on both the individual and society. Obesity Medicine focusses on health and disease, relating to the very broad spectrum of research in and impacting on humans. It is an interdisciplinary journal that addresses mechanisms of disease, epidemiology and co-morbidities. Obesity Medicine encompasses medical, societal, socioeconomic as well as preventive aspects of obesity and is aimed at researchers, practitioners and educators alike.
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